Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | PLK1 | P53350 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6854099 | 0.89 | PLK1 (0.48) | L3MBTL1MAPTALDH1A1KDM4EHTT | |
| SCHEMBL6850305 | 0.84 | MAPT (0.55) | L3MBTL1MAPTALDH1A1KDM4EHTT | |
| SCHEMBL6850072 | 0.84 | L3MBTL1 (0.43) | L3MBTL1MAPTALDH1A1KDM4EHTT | |
| SCHEMBL6853813 | 0.83 | L3MBTL1 (0.46) | L3MBTL1MAPTALDH1A1KDM4EHTT | |
| SCHEMBL6855314 | 0.83 | MAPT (0.54) | L3MBTL1MAPTALDH1A1KDM4EHTT | |
| SCHEMBL6854118 | 0.83 | L3MBTL1 (0.56) | L3MBTL1MAPTALDH1A1KDM4EHTT | |
| SCHEMBL6850068 | 0.82 | L3MBTL1 (0.48) | L3MBTL1MAPTALDH1A1KDM4EHTT | |
| SCHEMBL6853858 | 0.82 | L3MBTL1 (0.55) | L3MBTL1MAPTALDH1A1KDM4EHTT | |
| SCHEMBL6854997 | 0.82 | L3MBTL1 (0.48) | L3MBTL1MAPTALDH1A1KDM4EHTT | |
| SCHEMBL6855333 | 0.82 | L3MBTL1 (0.55) | L3MBTL1MAPTALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6828315-B1 | Anti- inflammatories, anti-allergics, bronchodilatators, anti-asthmatics, or TNF alpha inhibitors | WARNER-LAMBERT LLC | 2004-12-07 | — | — | US | claimed |
| EP-1177195-B1 | 1-AMINO TRIAZOLO 4,3-a! QUINAZOLINE-5-ONES AND OR -5-THIONES INHIBITING PHOSPHODIESTERASE IV | WARNER LAMBERT CO (US) | 2003-03-19 | — | — | EP | claimed |
| US-6828315-B1 | Anti- inflammatories, anti-allergics, bronchodilatators, anti-asthmatics, or TNF alpha inhibitors | WARNER-LAMBERT LLC | 2004-12-07 | — | — | US | disclosed |