SCHEMBL6854010

SCHEMBL6854010

COc1c(C=O)cc(C)c(C=O)c1OC

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 4/20 0.43
PRKDC P78527 1/20 0.41
ALDH1A1 P00352 3/20 0.41
TSHR P16473 2/20 0.41
KDM4E B2RXH2 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
ERN1 O75460 5/20 0.39
MCL1 Q07820 1/20 0.39
SRC P12931 1/20 0.38
TRIM24 O15164 1/20 0.35
TYR P14679 1/20 0.35
TRIM33 Q9UPN9 1/20 0.35
CYP19A1 P11511 1/20 0.34
NQO2 P16083 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29818737 0.86 PRKDC (0.40) AKR1B1PRKDCALDH1A1TSHRKDM4E
SCHEMBL26908584 0.86 AKR1B1 (0.36) AKR1B1PRKDCALDH1A1TSHRKDM4E
SCHEMBL13894661 0.83 ALDH1A1 (0.43) PRKDCALDH1A1TSHRKDM4ETDP1
SCHEMBL26908517 0.83 AKR1B1 (0.34) AKR1B1PRKDCALDH1A1TSHRKDM4E
SCHEMBL25342834 0.83 AKR1B1 (0.44) AKR1B1PRKDCALDH1A1TSHRKDM4E
SCHEMBL677316 0.80 CYP19A1 (0.46) AKR1B1PRKDCALDH1A1TSHRKDM4E
SCHEMBL25342401 0.78 PRKDC (0.40) AKR1B1PRKDCALDH1A1TSHRKDM4E
SCHEMBL27297143 0.78 ALDH1A1 (0.42) PRKDCALDH1A1TSHRKDM4ETDP1
SCHEMBL29818861 0.76 CA1 (0.47) AKR1B1PRKDCALDH1A1TSHRKDM4E
SCHEMBL29818735 0.76 ERN1 (0.46) AKR1B1PRKDCALDH1A1TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6783774-B1 Substance that stop any kind of bleeding within one second for medical, surgical, postsurgical and dental uses Song, Leslie B. 2004-08-31 US claimed
US-4780549-A ANTIOXIDANT FOR FOOD TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1988-10-25 US claimed
EP-0146121-B1 ASCORBIC ACID ETHERS AND THEIR PRODUCTION Takeda Chemical Industries, Ltd. (JP) 1988-08-17 EP claimed
EP-0146121-A2 Ascorbic acid ethers and their production Takeda Chemical Industries, Ltd. (JP) 1985-06-26 EP claimed
US-20240166867-A1 THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2024-05-23 US disclosed
EP-4286448-A1 THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-12-06 EP disclosed
CN-116940559-A Cyclic diol compound, process for producing the compound, and use of the compound 新日本理化株式会社 2023-10-24 CN disclosed
CN-116829618-A Thermoplastic resin and optical lens comprising the same 三菱瓦斯化学株式会社 2023-09-29 CN disclosed
WO-2022163674-A1 THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME 三菱瓦斯化学株式会社 2022-08-04 WO disclosed
WO-2022163684-A1 CYCLIC DIOL COMPOUND, METHOD FOR PRODUCING SAID COMPOUND, AND USE OF SAID COMPOUND 新日本理化株式会社 2022-08-04 WO disclosed
US-6783774-B1 Substance that stop any kind of bleeding within one second for medical, surgical, postsurgical and dental uses Song, Leslie B. 2004-08-31 US disclosed
US-4959362-A FREE RADICAL SCAVENGERS TAKEDA CHEMICAL INDUSTRIES, INC. (JP) 1990-09-25 US disclosed
US-4780549-A ANTIOXIDANT FOR FOOD TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1988-10-25 US disclosed
EP-0146121-B1 ASCORBIC ACID ETHERS AND THEIR PRODUCTION Takeda Chemical Industries, Ltd. (JP) 1988-08-17 EP disclosed
EP-0146121-A2 Ascorbic acid ethers and their production Takeda Chemical Industries, Ltd. (JP) 1985-06-26 EP disclosed