SCHEMBL6854918

SCHEMBL6854918

COCCCOc1cc(C[C@@H](C[C@H](NC(=O)OC(C)(C)C)[C@H](O)C[C@H](C(=O)NCC(C)(C)C(N)=O)C(C)C)C(C)C)ccc1OC

nearest known ligand 0.77

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13093701 1.00 REN (0.77) REN
SCHEMBL842334 1.00 REN (0.77) REN
SCHEMBL842335 1.00 REN (0.77) REN
SCHEMBL14641792 0.95 REN (0.69) REN
SCHEMBL12920947 0.94 REN (0.81) REN
SCHEMBL14476810 0.92 REN (0.76) REN
SCHEMBL4542652 0.92 REN (0.81) REN
SCHEMBL4542653 0.92 REN (0.81) REN
SCHEMBL16371079 0.92 REN (0.81) REN
SCHEMBL8280530 0.91 REN (0.84) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011064790-A1 A NOVEL PROCESS FOR MAKING ALISKIREN, ITS NOVEL INTERMEDIATES AND CERTAIN NOVEL COMPOUNDS Avra Laboratories Pvt. Ltd (IN) 2011-06-03 WO disclosed