Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 2/20 | 0.35 |
| ▸ | GABRD | O14764 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.35 |
| ▸ | GABRE | P78334 | 2/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.35 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8000398 | 0.84 | ALDH1A1 (0.38) | TP53ALDH1A1 | |
| SCHEMBL10901168 | 0.83 | SLC7A5 (0.32) | TP53SLC7A5 | |
| SCHEMBL10930954 | 0.83 | SLC7A5 (0.32) | TP53SLC7A5 | |
| SCHEMBL10901175 | 0.83 | SLC7A5 (0.32) | TP53SLC7A5 | |
| SCHEMBL5088264 | 0.78 | HCAR2 (0.36) | ALDH1A1 | |
| SCHEMBL5088265 | 0.78 | HCAR2 (0.36) | ALDH1A1 | |
| SCHEMBL10062317 | 0.77 | TP53 (0.40) | TP53GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL13567337 | 0.77 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL16673754 | 0.73 | TP53 (0.35) | TP53GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL2051254 | 0.73 | TP53 (0.35) | TP53GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011016052-A2 | PROCESS FOR PREPARING PREGABALIN | HELVETICA INDUSTRIES (P) LIMITED (IN) | 2011-02-10 | — | — | WO | disclosed |