Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5424673 | 0.82 | PIK3CD (0.54) | KMT2APOLBTDP1MEN1PKM | |
| SCHEMBL6855118 | 0.78 | HRH3 (0.42) | SMN1; SMN2 | |
| SCHEMBL10481722 | 0.78 | PIK3CD (0.50) | KMT2APOLBTDP1MEN1PKM | |
| SCHEMBL9625513 | 0.78 | GBA1 (0.33) | PKMRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL5697292 | 0.76 | PIK3CD (0.52) | KMT2APOLBTDP1MEN1PKM | |
| SCHEMBL31632694 | 0.76 | PIK3CD (0.52) | KMT2APOLBTDP1MEN1PKM | |
| SCHEMBL989008 | 0.76 | PIK3CD (0.52) | KMT2APOLBTDP1MEN1PKM | |
| SCHEMBL19514132 | 0.76 | PIK3CD (0.52) | KMT2APOLBTDP1MEN1PKM | |
| SCHEMBL261644 | 0.73 | PIK3CD (0.58) | KMT2AMEN1PKMPIK3CDTSHR | |
| SCHEMBL7265729 | 0.73 | CYP1A2 (0.55) | KMT2AMEN1PKMPIK3CDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6784293-B1 | SOLUTION AND SOLID-PHASE SYNTHESIS OF BOC-PROTECTED 3-AMINOHYDANTOINS/THIOHYDANTOINS AND 3-AMINODIHYDROURACILS/ DIHYDROTHIOURACILS | THE PROCTER & GAMBLE COMPANY | 2004-08-31 | — | — | US | disclosed |