Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.30 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6855141 | 0.78 | KMT2A (0.42) | ALDH1A1PKMRAB9ASMN1; SMN2 | |
| SCHEMBL6858200 | 0.77 | KEAP1 (0.42) | ALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL8660652 | 0.74 | — | — | |
| SCHEMBL6853955 | 0.74 | DRD2 (0.42) | — | |
| SCHEMBL6849961 | 0.67 | CYP1A2 (0.42) | — | |
| SCHEMBL6850095 | 0.66 | ALDH1A1 (0.38) | GBA1FAAHALDH1A1LMNATP53 | |
| SCHEMBL15805648 | 0.62 | GBA1 (0.42) | GBA1HSP90AA1FAAHALDH1A1TP53 | |
| SCHEMBL11853714 | 0.62 | GSK3A (0.45) | ALDH1A1LMNAPKMHPGDMAPK1 | |
| SCHEMBL4190795 | 0.60 | CRBN (0.46) | HSP90AA1TLR9FAAHALDH1A1LMNA | |
| SCHEMBL11257635 | 0.60 | CRBN (0.46) | HSP90AA1TLR9FAAHALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081091-A | For obtaining high molecular weight/narrow distribution addition homo- and copolymers by controlled bulk polymerization; silicon, germanium or tin organic compounds; cocatalysts | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-14 | — | — | US | disclosed |
| EP-0405787-A2 | Catalysts | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-02 | — | — | EP | disclosed |