Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3815320 | 0.82 | MAPT (0.46) | KMT2AMEN1POLBL3MBTL1LMNA | |
| SCHEMBL3176692 | 0.79 | MEN1 (0.50) | KMT2AMEN1PKMLMNAMAPT | |
| SCHEMBL3810329 | 0.79 | CA1 (0.46) | KMT2AMEN1PKMPOLBPTPN1 | |
| SCHEMBL3809482 | 0.74 | KMT2A (0.45) | KMT2AMEN1PKMPOLBPTPN1 | |
| SCHEMBL15568569 | 0.72 | MEN1 (0.50) | KMT2AMEN1PKMLMNAMAPT | |
| SCHEMBL3879022 | 0.72 | MEN1 (0.50) | KMT2AMEN1PKMLMNAMAPT | |
| SCHEMBL15568879 | 0.72 | MEN1 (0.50) | KMT2AMEN1PKMLMNAMAPT | |
| SCHEMBL3809816 | 0.72 | MEN1 (0.39) | KMT2AMEN1PKMPOLBLMNA | |
| SCHEMBL4859517 | 0.70 | MEN1 (0.58) | KMT2AMEN1PKMLMNAMAPT | |
| SCHEMBL3812077 | 0.70 | POLB (0.47) | KMT2AMEN1PKMPOLBPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6797712-B2 | Substituted amino-furan-2-yl-acetic acid and amino-thien-2-yl-acetic acid derivatives and their use in the treatment of migraine and pain | GRUENENTHAL GMBH (DE) | 2004-09-28 | — | — | US | disclosed |