Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.40 |
| ▸ | CDK2 | P24941 | 5/20 | 0.40 |
| ▸ | CDK7 | P50613 | 3/20 | 0.40 |
| ▸ | AKT1 | P31749 | 10/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 3/20 | 0.38 |
| ▸ | PAK4 | O96013 | 3/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6855694 | 1.00 | ATM (0.42) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6855907 | 0.89 | HDAC3 (0.42) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6855905 | 0.89 | HDAC3 (0.42) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5469830 | 0.86 | AKT1 (0.51) | ATMCDK2CDK7AKT1ROCK1 | |
| SCHEMBL5472198 | 0.81 | AKT1 (0.48) | ATMCDK2CDK7AKT1ROCK1 | |
| SCHEMBL5467193 | 0.79 | AKT1 (0.44) | CDK2CDK7AKT1ROCK1MAPK1 | |
| SCHEMBL4658342 | 0.78 | CDK2 (0.42) | CDK2CDK7AKT1ROCK1MAPK1 | |
| SCHEMBL6857876 | 0.78 | AKT1 (0.51) | CDK2CDK7AKT1ROCK1MAPK1 | |
| SCHEMBL14430184 | 0.78 | AKT1 (0.44) | CDK2CDK7AKT1ROCK1CSNK1D | |
| SCHEMBL6857879 | 0.78 | AKT1 (0.51) | CDK2CDK7AKT1ROCK1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831175-B2 | Such as N,N-dimethyl-N-(2-((5-((E)-2-pyridin-4-ylvinyl) pyridin-3-yl)oxy)ethyl)amine | ABBOTT LABORATORIES | 2004-12-14 | — | — | US | disclosed |
| US-20030199511-A1 | Kinase inhibitors | ABBVIE INC. | 2003-10-23 | — | — | US | disclosed |
| US-20030187026-A1 | Kinase inhibitors | ABBOTT LABORATORIES | 2003-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187026-A1 | Kinase inhibitors | MAP3K20, MAP3K19, MAP3K1 | ATM 353/4885HDAC3 3415/4885HDAC4 2680/4885 |
| US-20030199511-A1 | Kinase inhibitors | MAP3K20, MAP3K19, MAP3K1 | ATM 353/4885HDAC3 3415/4885HDAC4 2680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.