SCHEMBL685589

SCHEMBL685589

O=C1C=CC(O)C=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12168346 0.72 ALDH1A1 (0.50)
SCHEMBL11721399 0.67
SCHEMBL3262998 0.67 POLB (0.37)
SCHEMBL20402078 0.67
SCHEMBL10835193 0.67
SCHEMBL14108058 0.67
SCHEMBL3329042 0.67
SCHEMBL11819518 0.67
SCHEMBL2444081 0.67
Benzoquinone SCHEMBL8966070 0.65 TDP1 (0.80)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118146081-A Rhodium catalyzed construction of asymmetric 1, 3-diyne and conjugated eneyne compound and activity research thereof 重庆医科大学 2024-06-07 CN disclosed
US-11807796-B2 Heat transport device and heat transport method using same DAIKIN INDUSTRIES, LTD. (JP) 2023-11-07 US disclosed
US-11384071-B2 Inhibitors of mechanotransduction to treat pain and modulate touch perception MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN IN DER HELMHOLTZ-GEMEINSCHAFT (DE) 2022-07-12 US disclosed
US-20210299131-A1 TREATMENT OF NEURODEGENERATIVE DISEASES, CAUSATION OF MEMORY ENHANCEMENT, AND ASSAY FOR SCREENING COMPOUNDS FOR SUCH NATIONAL INSTITUTES OF HEALTH 2021-09-30 US disclosed
US-10953017-B2 Treatment of neurodegenerative diseases, causation of memory enhancement, and assay for screening compounds for such SOUTHERN RESEARCH INSTITUTE (US) 2021-03-23 US disclosed
US-20200171040-A1 TREATMENT OF NEURODEGENERATIVE DISEASES, CAUSATION OF MEMORY ENHANCEMENT, AND ASSAY FOR SCREENING COMPOUNDS FOR SUCH SOUTHERN RES INST (US) 2020-06-04 US disclosed
US-20190083505-A1 TREATMENT OF NEURODEGENERATIVE DISEASES, CAUSATION OF MEMORY ENHANCEMENT, AND ASSAY FOR SCREENING COMPOUNDS FOR SUCH NATIONAL INSTITUTES OF HEALTH 2019-03-21 US disclosed
US-9980969-B2 Treatment of neurodegenerative diseases, causation of memory enhancement, and assay for screening compounds for such SOUTHERN RESEARCH INSTITUTE (US) 2018-05-29 US disclosed
EP-2546907-B1 ELECTRODE ACTIVE MATERIAL FOR ELECTRICITY STORAGE DEVICE, AND ELECTRICITY STORAGE DEVICE USING THE SAME PANASONIC CORP (JP) 2016-11-23 EP disclosed
US-20160022691-A1 TREATMENT OF NEURODEGENERATIVE DISEASES, CAUSATION OF MEMORY ENHANCEMENT, AND ASSAY FOR SCREENING COMPOUNDS FOR SUCH SOUTHERN RES INST (US) 2016-01-28 US disclosed
US-8198096-B2 Sensor for detection of chemical warfare agents and explosives; polyacetylenes, polyarylenevinylenes; polymers contain hexafluoroisopropanol substituent MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2012-06-12 US disclosed
US-20110288063-A1 NOVEL FUSED BRIDGED BICYCLIC HETEROARYL SUBSTITUTED 6-ALKYLIDENE PENEMS AS POTENT BETA-LACTAMASE INHIBITORS NAEJA PHARMACEUTICAL INC. (CA) 2011-11-24 US disclosed
US-20110143197-A1 ELECTRODE ACTIVE MATERIAL FOR POWER STORAGE DEVICE AND POWER STORAGE DEVICE, AND ELECTRONIC EQUIPMENT AND TRANSPORTATION EQUIPMENT PANASONIC CORPORATION (JP) 2011-06-16 US disclosed
WO-2011047129-A1 TREATMENT OF NEURODEGENERATIVE DISEASES, CAUSATION OF MEMORY ENHANCEMENT, AND ASSAY FOR SCREENING COMPOUNDS FOR SUCH SOUTHERN RESEARCH INSTITUTE (US) 2011-04-21 WO disclosed
EP-2234191-A1 ELECTRODE ACTIVE MATERIAL FOR ELECTRIC STORAGE DEVICE, ELECTRIC STORAGE DEVICE, ELECTRONIC EQUIPMENT, AND TRANSPORTATION EQUIPMENT Panasonic Corporation (JP) 2010-09-29 EP disclosed
US-20100047688-A1 PHENANTHRENEQUINONE COMPOUND, ELECTRODE ACTIVE MATERIAL, AND POWER STORAGE DEVICE PANASONIC CORPORATION (JP) 2010-02-25 US disclosed
EP-1404659-B1 4-ARYL QUINOLS AND ANALOGS THEREOF AS THERAPEUTIC AGENTS CANCER REC TECH LTD (GB) 2010-02-10 EP disclosed
US-7569734-B2 Method of using rhodium quinonoid catalysts BROWN UNIVERSITY (US) 2009-08-04 US disclosed
US-4612401-A Process for the preparation of 4-hydroxy-2,4,6-trimethyl-2,5-cyclohexadienone RHONE-POULENC SANTE (FR) 1986-09-16 US disclosed
US-4560801-A FROM 2,4,6-YTRIMETHYLPHENOL, CHLORINE, ALKALI METAL HYDROXIDE, BICARBONATE, CARBONATE RHONE-POULENC SANTE (FR) 1985-12-24 US disclosed