SCHEMBL6856093

SCHEMBL6856093

CC(C)c1cc(C2(c3cc(C(C)C)c(N)c(C(C)C)c3)CCCCC2)cc(C(C)C)c1N

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.44
ALDH1A1 P00352 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
ESR1 P03372 4/20 0.37
ESR2 Q92731 4/20 0.37
SLC6A4 P31645 8/20 0.36
SLC6A3 Q01959 8/20 0.36
SLC6A2 P23975 5/20 0.36
EHMT2 Q96KQ7 1/20 0.32
KCNH2 Q12809 2/20 0.31
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL299796 0.81 ACHE (0.58) ACHEESR1ESR2SLC6A2
SCHEMBL31287197 0.74 ACHE (0.50) ACHEESR1ESR2SLC6A4SLC6A3
SCHEMBL297845 0.74 ACHE (0.50) ACHEESR1ESR2SLC6A4SLC6A3
SCHEMBL31287170 0.74 ACHE (0.50) ACHEALDH1A1L3MBTL1ESR1ESR2
SCHEMBL296625 0.74 ACHE (0.50) ACHEALDH1A1L3MBTL1ESR1ESR2
SCHEMBL7542751 0.74 ACHE (0.64) ACHEALDH1A1L3MBTL1ESR1ESR2
SCHEMBL298390 0.73 ESR1 (0.62) ACHEALDH1A1L3MBTL1ESR1ESR2
SCHEMBL29459439 0.73 ESR1 (0.62) ACHEALDH1A1L3MBTL1ESR1ESR2
SCHEMBL7909236 0.71 ACHE (0.39) ACHEALDH1A1ESR1ESR2
SCHEMBL7908940 0.71 ACHE (0.39) ACHEALDH1A1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6800774-B2 POLYNUCLEAR ALPHA-DIIMINE NICKEL(II) COMPLEX CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCE (CN) 2004-10-05 US disclosed
US-20020082162-A1 Catalysts used for olefine polymerization and the preparation thereof CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCE (CN) 2002-06-27 US disclosed