Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | RAD1 | O60671 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6856429 | 1.00 | KMT2A (0.34) | KMT2ACYP1A2CYP3A4CYP2D6MEN1 | |
| SCHEMBL6854475 | 0.99 | KMT2A (0.34) | KMT2ACYP1A2CYP3A4CYP2D6MEN1 | |
| SCHEMBL6854470 | 0.99 | KMT2A (0.34) | KMT2ACYP1A2CYP3A4CYP2D6MEN1 | |
| SCHEMBL6850186 | 0.92 | KMT2A (0.33) | KMT2ACYP1A2CYP3A4CYP2D6MEN1 | |
| SCHEMBL6996082 | 0.92 | KMT2A (0.33) | KMT2ACYP1A2CYP3A4CYP2D6MEN1 | |
| SCHEMBL6856178 | 0.90 | PLK1 (0.38) | KMT2ACYP3A4MEN1PKMMAPT | |
| SCHEMBL6856530 | 0.90 | PLK1 (0.38) | KMT2ACYP3A4MEN1PKMMAPT | |
| SCHEMBL6856532 | 0.90 | PLK1 (0.38) | KMT2ACYP3A4MEN1PKMMAPT | |
| SCHEMBL6855779 | 0.90 | PLK1 (0.38) | KMT2ACYP3A4MEN1PKMMAPT | |
| SCHEMBL6858253 | 0.90 | PLK1 (0.34) | KMT2AMEN1ALDH1A1PLK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6828315-B1 | Anti- inflammatories, anti-allergics, bronchodilatators, anti-asthmatics, or TNF alpha inhibitors | WARNER-LAMBERT LLC | 2004-12-07 | — | — | US | claimed |
| EP-1177195-B1 | 1-AMINO TRIAZOLO 4,3-a! QUINAZOLINE-5-ONES AND OR -5-THIONES INHIBITING PHOSPHODIESTERASE IV | WARNER LAMBERT CO (US) | 2003-03-19 | — | — | EP | claimed |
| JP-2002543199-A | — | — | 2002-12-17 | — | — | JP | claimed |
| EP-1177195-A1 | 1-AMINO TRIAZOLO 4,3-a! QUINAZOLINE-5-ONES AND OR -5-THIONES INHIBITING PHOSPHODIESTERASE IV | WARNER-LAMBERT COMPANY (US) | 2002-02-06 | — | — | EP | claimed |
| WO-2000066584-A1 | 1-AMINO TRIAZOLO¢4,3-a! QUINAZOLINE-5-ONES AND OR -5-THIONES INHIBITING PHOSPHODIESTERASE IV | WARNER-LAMBERT COMPANY (US) | 2000-11-09 | — | — | WO | claimed |
| US-6828315-B1 | Anti- inflammatories, anti-allergics, bronchodilatators, anti-asthmatics, or TNF alpha inhibitors | WARNER-LAMBERT LLC | 2004-12-07 | — | — | US | disclosed |
| EP-1177195-B1 | 1-AMINO TRIAZOLO 4,3-a! QUINAZOLINE-5-ONES AND OR -5-THIONES INHIBITING PHOSPHODIESTERASE IV | WARNER LAMBERT CO (US) | 2003-03-19 | — | — | EP | disclosed |
| US-20020119967-A1 | Pharmaceutical composition for preventing or treating a disease associated with an excess of IL-12-production | WARNER-LAMBERT COMPANY | 2002-08-29 | — | — | US | disclosed |
| WO-2002022112-A9 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING A DISEASE ASSOCIATED WITH AN EXCESS OF IL-12 PRODUCTION | WARNER LAMBERT CO (US) | 2002-06-06 | — | — | WO | disclosed |
| EP-1199074-A1 | Pharmaceutical composition for preventing or treating a disease associated with an excess of il-12 production | WARNER-LAMBERT COMPANY (US) | 2002-04-24 | — | — | EP | disclosed |
| EP-1188438-A1 | Pharmaceutical composition for preventing or treating a disease associated with an excess of Il-12 production | WARNER-LAMBERT COMPANY (US) | 2002-03-20 | — | — | EP | disclosed |