Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.48 |
| ▸ | AVPR1B | P47901 | 9/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | ATF4 | P18848 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6857215 | 0.91 | AVPR1B (0.55) | AXLAVPR1BHRH3 | |
| SCHEMBL6855434 | 0.91 | AVPR1B (0.55) | AXLAVPR1BHRH3 | |
| SCHEMBL6855696 | 0.89 | AXL (0.45) | AXLAVPR1BHRH3ATF4PDE3B | |
| SCHEMBL6856613 | 0.88 | HRH3 (0.48) | AXLAVPR1BHRH3ATF4TLR9 | |
| SCHEMBL6855437 | 0.88 | AVPR1B (0.49) | AXLAVPR1BHRH3ATF4PDE3B | |
| SCHEMBL6857032 | 0.84 | AVPR1B (0.48) | AXLAVPR1BHRH3ATF4 | |
| SCHEMBL6856988 | 0.84 | AVPR1B (0.53) | AVPR1BHRH3 | |
| SCHEMBL6857044 | 0.84 | AVPR1B (0.48) | AXLAVPR1BHRH3ATF4 | |
| SCHEMBL6857005 | 0.82 | AVPR1B (0.55) | AXLAVPR1BKCNH2 | |
| SCHEMBL6857168 | 0.82 | AVPR1B (0.46) | AXLAVPR1BHRH3ATF4PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011096461-A1 | QUINOLINE DERIVATIVE | 大正製薬株式会社 (JP) | 2011-08-11 | — | — | WO | disclosed |