Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4860614 | 0.92 | LMNA (0.37) | TSHRLMNAALDH1A1FGFR4 | |
| SCHEMBL10358045 | 0.90 | — | — | |
| SCHEMBL5081197 | 0.84 | LMNA (0.32) | TSHRLMNAALDH1A1FGFR4 | |
| SCHEMBL4860659 | 0.84 | LMNA (0.32) | TSHRLMNAALDH1A1FGFR4 | |
| SCHEMBL5081721 | 0.84 | LMNA (0.32) | TSHRLMNAALDH1A1FGFR4 | |
| SCHEMBL10358044 | 0.79 | — | — | |
| SCHEMBL3742820 | 0.79 | — | — | |
| SCHEMBL29217919 | 0.78 | — | — | |
| SCHEMBL179806 | 0.77 | — | — | |
| SCHEMBL15233344 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6777494-B1 | POLYTHIOURETHANE AND POLYTHIOETHER POLYMERS FORMED MAY BE USED ALONE OR MIXED FOR OPTICAL PURPOSES SUCH AS THE MANUFACTURE OF OPHTHALMIC LENSES | OPTIMA INC. | 2004-08-17 | — | — | US | disclosed |
| US-6008296-A | CURABLE MONOMER COMPOSITION COMPRISING A POLYISOCYANATE OR POLYTHIOISOCYANATE, POLYTHIOL, AND POLYENE OF GIVEN FORMULA; NO PHASE SEPERATION, SINGLE GLASS TRANSITION TEMPERATURE, IMPACT RESISTANCE AND HIGH REFRACTIVE INDEX FOR EYEGLASSES | OPTIMA, INC. (US) | 1999-12-28 | — | — | US | disclosed |