Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18801007 | 0.79 | ATR (0.31) | HTTKMT2ANOS3NOS1NOS2 | |
| SCHEMBL20124974 | 0.75 | NOS3 (0.54) | KMT2ANOS3NOS1NOS2 | |
| SCHEMBL30024828 | 0.75 | KMT2A (0.54) | HTTKMT2A | |
| SCHEMBL29950768 | 0.75 | ERN1 (0.39) | HTTKMT2ANOS3NOS1NOS2 | |
| SCHEMBL124004 | 0.75 | ERN1 (0.39) | HTTKMT2ANOS3NOS1NOS2 | |
| SCHEMBL24609208 | 0.75 | HTT (0.30) | HTTKMT2ANOS3NOS1NOS2 | |
| SCHEMBL247814 | 0.75 | ERN1 (0.39) | HTTKMT2ANOS3NOS1NOS2 | |
| SCHEMBL127596 | 0.75 | ERN1 (0.43) | HTT | |
| SCHEMBL124567 | 0.75 | KMT2A (0.54) | HTTKMT2A | |
| SCHEMBL12515434 | 0.75 | ERN1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011096461-A1 | QUINOLINE DERIVATIVE | 大正製薬株式会社 (JP) | 2011-08-11 | — | — | WO | disclosed |