SCHEMBL6856792

SCHEMBL6856792

CC(C)C[C@@H](N)c1ccc(F)cn1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APLNR P35414 2/20 0.46
AAK1 Q2M2I8 5/20 0.38
ALDH1A1 P00352 2/20 0.37
LMNA P02545 2/20 0.37
MAPT P10636 2/20 0.37
HTT P42858 2/20 0.37
HSD17B10 Q99714 2/20 0.37
PKM P14618 1/20 0.37
HPGD P15428 1/20 0.37
MAPK1 P28482 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
HRH1 P35367 1/20 0.35
KCNH2 Q12809 1/20 0.35
TAAR1 Q96RJ0 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
JAK2 O60674 1/20 0.33
JAK3 P52333 1/20 0.33
HTR2A P28223 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3770922 0.81 APLNR (0.45) APLNRHRH1KCNH2HDAC6
SCHEMBL588810 0.79 APLNR (0.53) APLNRHRH1KCNH2HDAC6MAOA
SCHEMBL475519 0.79 APLNR (0.53) APLNRHRH1KCNH2HDAC6MAOA
SCHEMBL347080 0.79 APLNR (0.53) APLNRHRH1KCNH2HDAC6MAOA
SCHEMBL1440342 0.78 APLNR (0.45) APLNRHRH1KCNH2HDAC6
SCHEMBL1440344 0.78 APLNR (0.45) APLNRHRH1KCNH2HDAC6
SCHEMBL1693712 0.77 APLNR (0.42) APLNRALDH1A1HRH1KCNH2HDAC6
Hydrochloric Acid SCHEMBL454779 0.77 APLNR (0.51) APLNRHRH1KCNH2HDAC6MAOA
Hydrochloric Acid SCHEMBL3230301 0.77 APLNR (0.51) APLNRHRH1KCNH2HDAC6MAOA
Hydrochloric Acid SCHEMBL1693822 0.77 APLNR (0.51) APLNRHRH1KCNH2HDAC6MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011013644-A1 SUBSTITUTED PIPERIDINE COMPOUND 第一三共株式会社 (JP) 2011-02-03 WO disclosed