Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.43 |
| ▸ | ACACB | O00763 | 2/20 | 0.41 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.40 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6855737 | 0.88 | HRH3 (0.47) | HRH3KCNH2ADRA1AAVPR1B | |
| SCHEMBL6856694 | 0.87 | HRH3 (0.41) | HRH3KCNH2ACACBAVPR1B | |
| SCHEMBL6856885 | 0.85 | HRH3 (0.44) | HRH3KCNH2ACACBAVPR1B | |
| SCHEMBL6856624 | 0.85 | AVPR1B (0.43) | HRH3KCNH2ACACBAVPR1B | |
| SCHEMBL6857472 | 0.81 | AVPR1B (0.51) | HRH3AVPR1B | |
| SCHEMBL6857432 | 0.81 | AVPR1B (0.43) | AVPR1B | |
| SCHEMBL6856705 | 0.80 | AVPR1B (0.58) | HRH3AVPR1B | |
| SCHEMBL6855979 | 0.80 | AVPR1B (0.39) | AVPR1B | |
| SCHEMBL6856235 | 0.79 | AVPR1B (0.39) | AVPR1B | |
| SCHEMBL6857222 | 0.79 | AVPR1B (0.42) | KCNH2AVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011096461-A1 | QUINOLINE DERIVATIVE | 大正製薬株式会社 (JP) | 2011-08-11 | — | — | WO | disclosed |