Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 4/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.38 |
| ▸ | CTSA | P10619 | 3/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | ICMT | O60725 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ESRRB | O95718 | 1/20 | 0.36 |
| ▸ | ESRRA | P11474 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6856235 | 0.89 | AVPR1B (0.39) | AVPR1BCTSADHODHTSPOABL1 | |
| SCHEMBL6856869 | 0.87 | AVPR1B (0.45) | AVPR1BESRRBESRRA | |
| SCHEMBL6857432 | 0.85 | AVPR1B (0.43) | AVPR1BICMT | |
| SCHEMBL6857370 | 0.83 | TRPV1 (0.39) | AVPR1BCTSAABL1SLC1A3SLC1A2 | |
| SCHEMBL6854936 | 0.83 | AVPR1B (0.41) | AVPR1B | |
| SCHEMBL6856891 | 0.81 | AVPR1B (0.40) | AVPR1BKDM4E | |
| SCHEMBL6856705 | 0.80 | AVPR1B (0.58) | AVPR1BESR1 | |
| SCHEMBL6856801 | 0.80 | HRH3 (0.43) | AVPR1B | |
| SCHEMBL6857500 | 0.80 | AVPR1B (0.41) | AVPR1B | |
| SCHEMBL6856813 | 0.79 | AVPR1B (0.40) | AVPR1BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011096461-A1 | QUINOLINE DERIVATIVE | 大正製薬株式会社 (JP) | 2011-08-11 | — | — | WO | disclosed |