Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 4/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | ACACB | O00763 | 5/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6857227 | 0.90 | HRH3 (0.48) | AVPR1BACACBHRH3 | |
| SCHEMBL6856915 | 0.90 | AVPR1B (0.40) | AVPR1B | |
| SCHEMBL6856694 | 0.89 | HRH3 (0.41) | AVPR1BACACBHRH3SLC6A4 | |
| SCHEMBL6856885 | 0.88 | HRH3 (0.44) | AVPR1BACACBHRH3 | |
| SCHEMBL6856624 | 0.88 | AVPR1B (0.43) | AVPR1BACACBHRH3 | |
| SCHEMBL6857457 | 0.88 | HRH1 (0.43) | ACACB | |
| SCHEMBL6856447 | 0.87 | ACACB (0.40) | AVPR1BACACBHRH3EPHX2 | |
| SCHEMBL6857218 | 0.87 | ACACB (0.45) | AVPR1BACACBHRH3 | |
| SCHEMBL6856195 | 0.84 | MALT1 (0.44) | ACACBHRH3EPHX2 | |
| SCHEMBL6856761 | 0.81 | AVPR1B (0.41) | AVPR1BEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011096461-A1 | QUINOLINE DERIVATIVE | 大正製薬株式会社 (JP) | 2011-08-11 | — | — | WO | disclosed |