Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 18/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6857488 | 0.90 | HRH3 (0.47) | AVPR1B | |
| SCHEMBL6856819 | 0.90 | AVPR1B (0.41) | AVPR1B | |
| SCHEMBL6856504 | 0.88 | HRH3 (0.43) | AVPR1BKCNH2 | |
| SCHEMBL6857222 | 0.87 | AVPR1B (0.42) | AVPR1BACVR1BTGFBR1ACVR1KCNH2 | |
| SCHEMBL6857409 | 0.82 | AVPR1B (0.43) | AVPR1B | |
| SCHEMBL6857383 | 0.81 | AVPR1B (0.42) | AVPR1B | |
| SCHEMBL6856267 | 0.79 | AVPR1B (0.46) | AVPR1B | |
| SCHEMBL6857227 | 0.79 | HRH3 (0.48) | AVPR1B | |
| SCHEMBL6857474 | 0.79 | AVPR1B (0.45) | AVPR1B | |
| SCHEMBL6856694 | 0.79 | HRH3 (0.41) | AVPR1BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011096461-A1 | QUINOLINE DERIVATIVE | 大正製薬株式会社 (JP) | 2011-08-11 | — | — | WO | disclosed |