Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6858745 | 1.00 | NPC1 (0.38) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL6854356 | 1.00 | NPC1 (0.38) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL6535039 | 0.94 | NPC1 (0.36) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL6534705 | 0.89 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL6856704 | 0.88 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL6534955 | 0.85 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL6534787 | 0.84 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL6535033 | 0.84 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL6850486 | 0.81 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL6534731 | 0.80 | NPC1 (0.38) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6783812-B2 | USEFUL IN THE MANUFACTURE OF OPTICAL DEVICES; STABILITY | DISPLAYTECH, INC. | 2004-08-31 | — | — | US | disclosed |
| US-20020130299-A1 | Alkyl silane liquid crystal compounds | CITIZEN FINEDEVICE CO., LTD. (JP) | 2002-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020130299-A1 | Alkyl silane liquid crystal compounds | SMURF1, SMURF2, DSTN | NPC1 2373/4885RAB9A 3181/4885SMN1; SMN2 2052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.