SMURF1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL17256444	1.00	20/20
SCHEMBL17256445	1.00	20/20
SCHEMBL17256450	1.00	20/20
SCHEMBL17256451	1.00	20/20
SCHEMBL17256454	1.00	20/20
SCHEMBL17256456	1.00	20/20
SCHEMBL17256463	1.00	20/20
SCHEMBL17256467	1.00	20/20
SCHEMBL17256474	1.00	20/20
SCHEMBL17256479	1.00	20/20
SCHEMBL17256482	1.00	20/20
SCHEMBL17256486	1.00	20/20
SCHEMBL17256489	1.00	20/20
SCHEMBL17256492	1.00	20/20
SCHEMBL17256493	1.00	20/20
SCHEMBL17256495	1.00	20/20
SCHEMBL17256498	1.00	20/20
SCHEMBL17256499	1.00	20/20
SCHEMBL17256502	1.00	20/20
SCHEMBL17256504	1.00	20/20

Clinical trials — most relevant to SMURF1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Can We Achieve 'high-quality' Weight Loss Through Supplementation and Exercise? the TRIM MUSCLE Study	PHASE3	COMPLETED
Strategies to Reduce Organic Muscle Atrophy in the Intensive Care Unit	PHASE2/PHASE3	WITHDRAWN
Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers	PHASE2	NOT_YET_RECRUITING
Alrizomadlin (APG-115) in Subjects With BAP1 Cancer Syndrome and Early-Stage Mesothelioma	PHASE2	WITHDRAWN
Nilotinib in Huntington's Disease	PHASE1	UNKNOWN
PS-341 and Radiation to Treat Advanced Cancer of the Head and Neck	PHASE1	COMPLETED
Smurf2 Gene Expression in Urinary Tract Tumors	nan	UNKNOWN
SMYD3-Driven Metabolic Rewiring in Colorectal Liver Metastases	nan	NOT_YET_RECRUITING
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
Clinical Study of 68Ga-DOTA-BLP PET Imaging in Noninvasive Diagnosis of Malignant Tumors	nan	NOT_YET_RECRUITING
Genetic Variation in TRAF3IP2 (rs13190932)	nan	RECRUITING
Establishment of a Prospective Clinical-biological Database	nan	RECRUITING
Transcripts with Retained H/ACA Box SnoRNA Sequences As Biomarkers for Estrogen Dependence in Lum-B Breast Carcinomas	nan	ACTIVE_NOT_RECRUITING
Studying The Role of Key Epigenetic Mediators in Breast Cancer Patients	nan	RECRUITING
Mitochondrial Activity and Myosteatosis in the Cachexia of Cancers of the Upper Aerodigestive Tract	nan	UNKNOWN
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis	nan	UNKNOWN
Beta-Hydroxy-Beta-Methylbutyrate (HMB) Supplementation After Liver Transplantation	nan	COMPLETED
Exploring Novel Biomarkers of ICU-AW in Mechanically Ventilated Children at the Molecular Level	nan	ENROLLING_BY_INVITATION
Diagnostic Potential of UCHL1 in Acute Decompensated Heart Failure	nan	COMPLETED
Effect of Dietary Nitrate on Immobilization-induced Changes in Skeletal Muscle in Young Healthy Men	nan	RECRUITING
The Molecular Pathogenesis Study of Cataract	nan	UNKNOWN
Evaluation of Prognostic Factors: From Breast Cancer to Bone Metastases	nan	UNKNOWN
Genetic Factors Affecting the Severity of Beta Thalassemia	nan	COMPLETED
The Role of RING Ubiquitin Ligases in Biologic and Oncologic Processes in Tissues of Mesenchymal Origin	nan	UNKNOWN
Study on the Pathogenesis and Reversal Strategies of Cancer Cachexia Based on Multi-Omics	nan	RECRUITING
Maximizing Mechanisms of Muscle Hypertrophy to Combat Sarcopenia in Older Adults	nan	COMPLETED
Molecular Profile of the Evolution of Inclusion Body Myositis	nan	COMPLETED
Circulating Non-coding RNAs and Cardiovascular Outcomes in Patients With Dyslipidemia and Atherosclerosis	nan	UNKNOWN
Identification of a New Blood Biomarker for the Diagnosis and Prognosis of Liposarcomas	nan	RECRUITING
Long Term Follow-Up of Patients With Mesothelioma and Individuals With Germline Mutations in BAP1	nan	RECRUITING

Related proteins — ESM-2 sequence neighbours (a SMURF1 binder may also engage these)

Protein	Name	Similarity
Q9PUN2	—	1.000	Q9PUN2 →
Q9CUN6	—	1.000	Q9CUN6 →
SMURF2	E3 ubiquitin-protein ligase SMURF2	1.000	landscape →
A9JRZ0	—	0.999	A9JRZ0 →
Q2TAS2	—	0.999	Q2TAS2 →
Q9DBH0	—	0.998	Q9DBH0 →
Q62940	—	0.997	Q62940 →
A2A5Z6	—	0.996	A2A5Z6 →
Q9H0M0	—	0.996	Q9H0M0 →
Q5RBF2	—	0.995	Q5RBF2 →
Q8C863	—	0.995	Q8C863 →
Q8BZZ3	—	0.995	Q8BZZ3 →
P46935	—	0.994	P46935 →
B8N7E5	—	0.994	B8N7E5 →
Q96PU5	—	0.994	Q96PU5 →
Q9N2Z7	—	0.993	Q9N2Z7 →
Q2UBP1	—	0.993	Q2UBP1 →
Q8CFI0	—	0.993	Q8CFI0 →
O00308	—	0.993	O00308 →
Q9Y0H4	—	0.992	Q9Y0H4 →
A1CQG2	—	0.989	A1CQG2 →
P39940	—	0.989	P39940 →
A1D3C5	—	0.989	A1D3C5 →
Q92462	—	0.989	Q92462 →
Q5BJS0	—	0.989	Q5BJS0 →
G0S9J5	—	0.989	G0S9J5 →
ITCH	E3 ubiquitin-protein ligase Itchy homolog	0.989	landscape →
Q9UTG2	—	0.988	Q9UTG2 →
NFKB1	Nuclear factor NF-kappa-B p105 subunit	0.988	landscape →
B0R0W9	—	0.988	B0R0W9 →