Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954366 | 0.83 | TDP1 (0.35) | ERN1TDP1PIK3CDSIRT6CYP1A2 | |
| SCHEMBL10322950 | 0.83 | TDP1 (0.35) | ERN1TDP1PIK3CDSIRT6CYP1A2 | |
| SCHEMBL26180499 | 0.79 | ERN1 (0.34) | ERN1TDP1SIRT6CYP1A2CYP3A4 | |
| SCHEMBL1533918 | 0.78 | TDP1 (0.40) | ERN1TDP1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30589401 | 0.78 | TDP1 (0.40) | ERN1TDP1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL24458114 | 0.75 | ERN1 (0.35) | ERN1TDP1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14327941 | 0.75 | UHRF1 (0.54) | ERN1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL21728724 | 0.75 | UHRF1 (0.30) | ERN1UHRF1 | |
| SCHEMBL1389512 | 0.75 | ERN1 (0.48) | ERN1TDP1 | |
| SCHEMBL29954903 | 0.75 | ERN1 (0.35) | ERN1TDP1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| WO-2021014415-A2 | SMALL MOLECULE INHIBITORS OF ACETYL COENZYME A SYNTHETASE SHORT CHAIN 2 (ACSS2) | CURADEV PHARMA PVT. LTD. (IN) | 2021-01-28 | — | — | WO | disclosed |
| WO-2011096461-A1 | QUINOLINE DERIVATIVE | 大正製薬株式会社 (JP) | 2011-08-11 | — | — | WO | disclosed |