Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL47975 | 0.79 | IDO1 (0.58) | IDO1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10369113 | 0.79 | IDO1 (0.58) | IDO1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7888003 | 0.76 | IDO1 (0.69) | IDO1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL29984975 | 0.76 | IDO1 (0.69) | IDO1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL165560 | 0.76 | IDO1 (0.69) | IDO1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4110103 | 0.72 | IDO1 (0.54) | IDO1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL895205 | 0.72 | IDO1 (0.54) | IDO1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL29439097 | 0.72 | IDO1 (0.54) | IDO1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL249746 | 0.72 | IDO1 (0.54) | IDO1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL30956678 | 0.72 | IDO1 (0.54) | IDO1CYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6790968-B1 | ENHANCES ACTIVITY OF AZOLE ANTIFUNGAL AGENTS; TREATMENT OF DEEP-SEATED MYCOSIS; CULTURING TALAROMYCES FLAVUS | THE KITASATO INSTITUTE (JP) | 2004-09-14 | — | — | US | disclosed |