SCHEMBL165560

SCHEMBL165560

Clc1ccc(COOCc2ccc(Cl)cc2Cl)c(Cl)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.69
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2C9 P11712 1/20 0.56
MAPK1 P28482 1/20 0.56
CYP2C19 P33261 1/20 0.56
NR4A2 P43354 2/20 0.50
HTT P42858 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.49
CHRNB2 P17787 1/20 0.49
CHRNA4 P43681 1/20 0.49
NR4A1 P22736 1/20 0.46
NR4A3 Q92570 1/20 0.46
GAA P10253 1/20 0.46
TP53 P04637 1/20 0.46
TSHR P16473 1/20 0.45
CASP3 P42574 1/20 0.45
KMT2A Q03164 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
SENP8 Q96LD8 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29984975 1.00 IDO1 (0.69) IDO1CYP1A2CYP3A4CYP2C9MAPK1
SCHEMBL11002124 0.92 IDO1 (0.60) IDO1CYP1A2CYP3A4CYP2C9MAPK1
SCHEMBL7888003 0.86 IDO1 (0.69) IDO1CYP1A2CYP3A4CYP2C9MAPK1
SCHEMBL3156683 0.83 IDO1 (0.60) IDO1CYP1A2CYP3A4CYP2C9MAPK1
SCHEMBL11157965 0.82 IDO1 (0.64) IDO1CYP1A2CYP3A4CYP2C9MAPK1
SCHEMBL11129339 0.82 IDO1 (0.64) IDO1CYP1A2CYP3A4CYP2C9MAPK1
SCHEMBL1989190 0.82 IDO1 (0.64) IDO1CYP1A2CYP3A4CYP2C9MAPK1
SCHEMBL1989192 0.82 IDO1 (0.64) IDO1CYP1A2CYP3A4CYP2C9MAPK1
SCHEMBL9767549 0.82 IDO1 (1.00) IDO1CYP1A2CYP3A4CYP2C9MAPK1
SCHEMBL5079167 0.82 IDO1 (0.64) IDO1CYP1A2CYP3A4CYP2C9MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 695 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240326361-A1 SEALANT COMPOSITION FOR SELF-SEALING PNEUMATIC TIRE THE GOODYEAR TIRE & RUBBER COMPANY 2024-10-03 US claimed
EP-4438280-A1 SEALANT COMPOSITION FOR SELF-SEALING PNEUMATIC TIRE The Goodyear Tire & Rubber Company (US) 2024-10-02 EP claimed
EP-3658617-A1 VULCANIZABLE COMPOSITIONS COMPRISING HYDROGENATED NITRILE-DIENE-CARBOXYLIC ESTER COPOLYMER AND SILICA ARLANXEO Deutschland GmbH (DE) 2020-06-03 EP claimed
US-20200140595-A1 Vulcanizable Compositions Comprising Hydrogenated Nitrile-Diene-Carboxylic Ester Copolymer and Silica ARLANXEO DEUTCHLAND GMBH (DE) 2020-05-07 US claimed
CN-110914352-A Curable composition containing hydrogenated nitrile-diene-carboxylate copolymer and silica 阿朗新科德国有限责任公司 2020-03-24 CN claimed
US-10589478-B2 Pneumatic tire having sealant layer Triangle Tyre Co. Ltd. (CN) 2020-03-17 US claimed
US-10563039-B2 Compositions and methods for crosslinking polymers in the presence of atmospheric oxygen ARKEMA INC. (US) 2020-02-18 US claimed
EP-3562877-A1 RUBBER MIXTURES ARLANXEO Deutschland GmbH (DE) 2019-11-06 EP claimed
WO-2019020392-A1 VULCANIZABLE COMPOSITIONS COMPRISING HYDROGENATED NITRILE-DIENE-CARBOXYLIC ESTER COPOLYMER AND SILICA ARLANXEO DEUTSCHLAND GMBH (DE) 2019-01-31 WO claimed
WO-2018121976-A1 RUBBER MIXTURES ARLANXEO DEUTSCHLAND GMBH (DE) 2018-07-05 WO claimed
US-20040133025-A1 Method of making mercaptoalkylalkyldialkoxysilanes DOW CORNING CORPORATION 2004-07-08 US claimed
US-20040071909-A1 Accelerator-free thin-walled rubber vulcanizates from latex APEX MEDICAL TECHNOLOGIES, INC., A CORPORATION OF THE STATE OF ILLINOIS 2004-04-15 US claimed
US-20030230376-A1 Self-sealing pneumatic tire and preparation thereof GOODYEAR TIRE & RUBBER COMPANY, THE 2003-12-18 US claimed
US-6573333-B2 Wherein there is no phase segregation; moldings characterized by improved mechanical properties and better resistance in mineral oils; profiles, belts, rings, seals, damping elements, coatings, coverings BAYER AKTIENGESELLSCHAFT (DE) 2003-06-03 US claimed
US-6300421-B1 BLENDING ELASTOMER, REINFORCEMENT SELECTED FROM CLAY, CARBON BLACK, SILICA, PEROXIDE CURING AGENT, ACRYLATE CO-CURING AGENT, ELEMENTAL SULPHUR CURING AGENT; HEATING AND CURING THE GOODYEAR TIRE & RUBBER COMPANY 2001-10-09 US claimed
EP-1033386-A1 Preparation of peroxide vulcanized rubber composition and articles having at least one component thereof THE GOODYEAR TIRE & RUBBER COMPANY (US) 2000-09-06 EP claimed
US-5597853-A IMPROVED CREPE HARDENING AND SHELF STABILITY SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-01-28 US claimed
EP-0571435-B1 INSULATED WINDING, PROCESS FOR PRODUCING IT, AND SEMI-FINISHED PRODUCT USED IN THE PRODUCTION PROCESS MODERNE MASCHINEN APPARATE WER (CH) 1996-10-23 EP claimed
US-4895610-A LAYER OF BUTYL RUBBER, POLYISOBUTYLENE, OIL EXTENDER, PEROXIDE, SULFUR THE GOODYEAR TIRE & RUBBER COMPANY (US) 1990-01-23 US claimed
US-4346185-A Process for the production of alkali metal unsaturated polyester silicate resinous products BLOUNT DAVID H 1982-08-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040133025-A1 Method of making mercaptoalkylalkyldialkoxysilanes MPST, TST, MSMO1 IDO1 1357/4885CYP1A2 629/4885CYP3A4 502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.