Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 10/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.64 |
| ▸ | CETP | P11597 | 8/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6855337 | 0.95 | SLC6A2 (0.61) | SLC6A2SLC6A4CETPSLC6A3LMNA | |
| SCHEMBL993643 | 0.94 | SLC6A2 (0.61) | SLC6A2SLC6A4CETPSLC6A3LMNA | |
| SCHEMBL993065 | 0.94 | SLC6A2 (0.60) | SLC6A2SLC6A4CETPSLC6A3LMNA | |
| SCHEMBL995561 | 0.86 | SLC6A2 (0.53) | SLC6A2SLC6A4CETPSLC6A3LMNA | |
| SCHEMBL993969 | 0.85 | SLC6A2 (0.51) | SLC6A2SLC6A4CETPSLC6A3LMNA | |
| SCHEMBL992981 | 0.83 | SLC6A2 (0.49) | SLC6A2SLC6A4CETPSCN9A | |
| SCHEMBL992716 | 0.83 | SLC6A2 (0.54) | SLC6A2SLC6A4CETPSLC6A3LMNA | |
| SCHEMBL5993372 | 0.78 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6857794 | 0.78 | CETP (0.54) | SLC6A2SLC6A4CETPSLC6A3 | |
| SCHEMBL6858407 | 0.77 | CETP (0.70) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787570-B2 | ADMINISTERING AN AROMATIC OR HETEROAROMATIC SUBSTITUTED TERTIARYAMINE COMPOUND TO TREAT ATHEROSCLEROSIS, DYSLIPIDEMIA, AND OTHER CORONARY ARTERY DISEASES | PFIZER, INC. | 2004-09-07 | — | — | US | claimed |