Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 15/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6858407 | 0.85 | CETP (0.70) | CETP | |
| SCHEMBL6855335 | 0.81 | CETP (0.67) | CETP | |
| SCHEMBL993642 | 0.81 | CETP (0.63) | CETP | |
| SCHEMBL6857797 | 0.78 | SLC6A2 (0.64) | CETPSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5995736 | 0.76 | SLC6A2 (0.73) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3397214 | 0.76 | PYCR1 (0.41) | SLC6A2SLC6A4TSHR | |
| SCHEMBL993968 | 0.74 | CETP (0.57) | CETP | |
| SCHEMBL992980 | 0.73 | CETP (0.56) | CETP | |
| SCHEMBL6855337 | 0.73 | SLC6A2 (0.61) | CETPSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL995559 | 0.73 | CETP (0.59) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787570-B2 | ADMINISTERING AN AROMATIC OR HETEROAROMATIC SUBSTITUTED TERTIARYAMINE COMPOUND TO TREAT ATHEROSCLEROSIS, DYSLIPIDEMIA, AND OTHER CORONARY ARTERY DISEASES | PFIZER, INC. | 2004-09-07 | — | — | US | claimed |