SCHEMBL6857940

SCHEMBL6857940

CCCCN([Si](C)(C)C)[Si](C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
LMNA P02545 1/20 0.35
DNM1 Q05193 3/20 0.35
CA12 O43570 3/20 0.33
CA1 P00915 3/20 0.33
CA9 Q16790 3/20 0.33
ALDH1A1 P00352 1/20 0.33
ALDH2 P05091 1/20 0.33
THRB P10828 1/20 0.33
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP3 P08254 1/20 0.31
MMP8 P22894 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4641310 0.89
SCHEMBL6857828 0.88 DNM1 (0.50) TSHRLMNADNM1CA12CA1
SCHEMBL22116238 0.88 DNM1 (0.50) TSHRLMNADNM1CA12CA1
SCHEMBL6851065 0.88 DNM1 (0.50) TSHRLMNADNM1CA12CA1
SCHEMBL30841641 0.88 DNM1 (0.50) TSHRLMNADNM1CA12CA1
SCHEMBL23778608 0.88 DNM1 (0.50) TSHRLMNADNM1CA12CA1
SCHEMBL3873514 0.88 DNM1 (0.50) TSHRLMNADNM1CA12CA1
SCHEMBL22116235 0.88 DNM1 (0.50) TSHRLMNADNM1CA12CA1
SCHEMBL30841446 0.88 DNM1 (0.50) TSHRLMNADNM1CA12CA1
SCHEMBL6859258 0.88 DNM1 (0.50) TSHRLMNADNM1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8962745-B2 Functionalized polymers and vulcanizates with reduced hysteretic loss BRIDGESTONE CORPORATION (JP) 2015-02-24 US claimed
EP-3873953-B1 PROCESS FOR THE PREPARATION OF POLYETHYLENES SABIC GLOBAL TECHNOLOGIES BV (NL) 2024-10-16 EP disclosed
US-11952440-B2 Process for the preparation of polyethylenes SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2024-04-09 US disclosed
US-20210371553-A1 PROCESS FOR THE PREPARATION OF POLYETHYLENES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-12-02 US disclosed
EP-3873953-A1 PROCESS FOR THE PREPARATION OF POLYETHYLENES SABIC Global Technologies B.V. (NL) 2021-09-08 EP disclosed
US-6737193-B2 ACTIVE MATERIALS IN THE POSITIVE ELECTRODES OF BATTERIES. NOVEL METHODS FOR PREPARING THE TETRAKETOPIPERAZINE UNIT-CONTAINING COMPOUNDS INCLUDE: (I) REACTING AN OXALYL HALIDE AND AN OXAMIDE, AND ADDING WATER OR AN AQUEOUS ALKALI IM&T RESEARCH, INC. 2004-05-18 US disclosed
US-20030148188-A1 Active materials in the positive electrodes of batteries. Novel methods for preparing the tetraketopiperazine unit-containing compounds include: (i) reacting an oxalyl halide and an oxamide, and adding water or an aqueous alkali IM&T RESEARCH, INC. 2003-08-07 US disclosed