SCHEMBL6858049

SCHEMBL6858049

C[Si](N)(c1ccccc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
TSHR P16473 4/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
ALDH1A1 P00352 3/20 0.36
ACHE P22303 2/20 0.36
KDM4E B2RXH2 2/20 0.36
GLA P06280 2/20 0.36
HPGD P15428 2/20 0.36
CASP1 P29466 2/20 0.36
CASP7 P55210 2/20 0.36
HSD17B10 Q99714 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
CHRM2 P08172 1/20 0.36
ADRA2A P08913 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
CHRM1 P11229 1/20 0.36
NQO2 P16083 1/20 0.36
MAOA P21397 1/20 0.36
DRD1 P21728 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL843029 0.81 ESR1 (0.44) ESR1ESR2TSHRSMN1; SMN2ALDH1A1
SCHEMBL8194001 0.77 ESR1 (0.41) ESR1ESR2TSHRSMN1; SMN2ALDH1A1
SCHEMBL2796775 0.75 ESR1 (0.44) ESR1ESR2TSHRSMN1; SMN2ALDH1A1
SCHEMBL1494255 0.75 ESR1 (0.44) ESR1ESR2TSHRSMN1; SMN2ALDH1A1
SCHEMBL49539 0.73 TSHR (0.39) ESR1ESR2TSHRSMN1; SMN2ALDH1A1
SCHEMBL7877395 0.73 TSHR (0.47) ESR1ESR2TSHRSMN1; SMN2ALDH1A1
SCHEMBL3900193 0.73 TSHR (0.39) ESR1ESR2TSHRSMN1; SMN2ALDH1A1
SCHEMBL239179 0.73 ESR1 (0.48) ESR1ESR2TSHRSMN1; SMN2ALDH1A1
SCHEMBL2169977 0.73 ESR1 (0.48) ESR1ESR2TSHRSMN1; SMN2ALDH1A1
SCHEMBL92396 0.73 ESR1 (0.48) ESR1ESR2TSHRSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240368427-A1 CURABLE RESIN COMPOSITION, CURED PRODUCT, ELECTRONIC COMPONENT, OPTICAL COMPONENT, AND COMPOSITE MEMBER JNC CORPORATION (JP) 2024-11-07 US disclosed
EP-4386053-A2 SILOXANE POLYMER COMPOSITION, CURED PRODUCT, ELECTRONIC COMPONENT, OPTICAL COMPONENT, AND COMPOSITE MEMBER JNC Corporation (JP) 2024-06-19 EP disclosed
CN-117795010-A Silicone polymer composition, cured product, electronic component, optical component, and composite member 捷恩智株式会社 2024-03-29 CN disclosed
WO-2022215759-A2 SILOXANE POLYMER COMPOSITION, CURED PRODUCT, ELECTRONIC COMPONENT, OPTICAL COMPONENT, AND COMPOSITE MEMBER JNC株式会社 2022-10-13 WO disclosed
US-10669422-B2 Condensation-curable silicone resin composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-06-02 US disclosed
US-20180051138-A1 CONDENSATION-CURABLE SILICONE RESIN COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-02-22 US disclosed
EP-3284788-A1 CONDENSATION-CURABLE SILICONE RESIN COMPOSITION Shin-Etsu Chemical Co., Ltd. (JP) 2018-02-21 EP disclosed
CN-103857725-A Polymer compound and electronic element SUMITOMO CHEMICAL CO 2014-06-11 CN disclosed
CN-103597005-A Polymer compound, and electronic element using same SUMITOMO CHEMICAL CO 2014-02-19 CN disclosed
CN-103270076-A Polymer compound containing carbon cluster structure and organic device using same SUMITOMO CHEMICAL CO 2013-08-28 CN disclosed
CN-101048465-B Polymeric luminescent material composition and polymeric light-emitting device SUMITOMO CHEMICAL CO 2011-02-16 CN disclosed
CN-1863838-B Polymeric light-emitting material and polymeric light-emitting element SUMITOMO CHEMICAL CO 2010-12-22 CN disclosed
CN-101624397-A Luminescent-polymer composition SUMITOMO CHEMICAL CO 2010-01-13 CN disclosed
CN-100516165-C Luminescent polymer composition SUMITOMO CHEMICAL CO (JP) 2009-07-22 CN disclosed
CN-101048465-A Polymeric luminescent material composition and polymeric light-emitting device SUMITOMO CHEMICAL CO (JP) 2007-10-03 CN disclosed
CN-1989169-A Polymer compound, polymer film, and polymer film element using same SUMITOMO CHEMICAL CO (JP) 2007-06-27 CN disclosed
CN-1863838-A Polymeric light-emitting material and polymeric light-emitting element SUMITOMO CHEMICAL CO (JP) 2006-11-15 CN disclosed
CN-1788068-A Luminescent polymer composition SUMITOMO CHEMICAL CO (JP) 2006-06-14 CN disclosed
US-6737193-B2 ACTIVE MATERIALS IN THE POSITIVE ELECTRODES OF BATTERIES. NOVEL METHODS FOR PREPARING THE TETRAKETOPIPERAZINE UNIT-CONTAINING COMPOUNDS INCLUDE: (I) REACTING AN OXALYL HALIDE AND AN OXAMIDE, AND ADDING WATER OR AN AQUEOUS ALKALI IM&T RESEARCH, INC. 2004-05-18 US disclosed
US-20030148188-A1 Active materials in the positive electrodes of batteries. Novel methods for preparing the tetraketopiperazine unit-containing compounds include: (i) reacting an oxalyl halide and an oxamide, and adding water or an aqueous alkali IM&T RESEARCH, INC. 2003-08-07 US disclosed