SCHEMBL2169977

SCHEMBL2169977

C[Si](c1ccccc1)(c1ccccc1)[Si](C)(c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.48
ESR2 Q92731 1/20 0.48
TSHR P16473 3/20 0.39
ACHE P22303 2/20 0.39
LMNA P02545 1/20 0.39
ALOX12 P18054 1/20 0.39
NR1H2 P55055 2/20 0.38
NR1H3 Q13133 2/20 0.38
MAPT P10636 1/20 0.37
ALDH1A1 P00352 1/20 0.35
NPC1 O15118 3/20 0.35
RAB9A P51151 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
TP53 P04637 1/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
MAPK1 P28482 1/20 0.33
CA4 P22748 1/20 0.33
BRD4 O60885 1/20 0.32
BRD2 P25440 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL242201 0.87 ESR1 (0.44) ESR1ESR2TSHRACHELMNA
SCHEMBL11023948 0.87 ESR1 (0.44) ESR1ESR2TSHRACHELMNA
SCHEMBL14666537 0.84 ESR1 (0.42) ESR1ESR2TSHRACHELMNA
SCHEMBL10150936 0.84 ESR1 (0.42) ESR1ESR2TSHRACHELMNA
SCHEMBL9138483 0.82 ESR1 (0.41) ESR1ESR2TSHRACHELMNA
SCHEMBL10613820 0.82 ESR1 (0.41) ESR1ESR2TSHRACHELMNA
SCHEMBL63526 0.79 ESR1 (0.70) ESR1ESR2TSHRACHELMNA
SCHEMBL239179 0.79 ESR1 (0.48) ESR1ESR2TSHRACHELMNA
SCHEMBL439492 0.79 ESR1 (0.48) ESR1ESR2TSHRACHELMNA
SCHEMBL92396 0.79 ESR1 (0.48) ESR1ESR2TSHRACHELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10422036-B2 Suppressing aging of platinum group metal particles in a catalytic converter GM Global Technology Operations LLC (US) 2019-09-24 US claimed
CN-106607103-B Inhibit the aging of platinum group metal particles in catalytic converter 通用汽车环球科技运作有限责任公司 2019-08-27 CN claimed
CN-106607103-A SUPPRESSING AGING OF PLATINUM GROUP METAL PARTICLES IN CATALYTIC CONVERTER 通用汽车环球科技运作有限责任公司 2017-05-03 CN claimed
US-20170114458-A1 SUPPRESSING AGING OF PLATINUM GROUP METAL PARTICLES IN A CATALYTIC CONVERTER GM Global Technology Operations LLC 2017-04-27 US claimed
US-9216952-B2 Process for preparing antiviral compound ABBVIE INC. (US) 2015-12-22 US claimed
EP-2411372-B1 PROCESS FOR PREPARING AN ANTIVIRAL COMPOUND ABBVIE BAHAMAS LTD (BS) 2014-07-23 EP claimed
US-20110237793-A1 PROCESS FOR PREPARING ANTIVIRAL COMPOUND ABBOTT LABORATORIES (US) 2011-09-29 US claimed
EP-0067066-B2 Dry-developing resist composition FUJITSU LTD (JP) 1994-01-12 EP claimed
EP-0067066-B1 DRY-DEVELOPING RESIST COMPOSITION FUJITSU LIMITED (JP) 1985-12-18 EP claimed
EP-0067067-B1 DRY-DEVELOPING NEGATIVE RESIST COMPOSITION FUJITSU LIMITED (JP) 1985-09-25 EP claimed
US-4481279-A Dry-developing resist composition FUJITSU LIMITED (JP) 1984-11-06 US claimed
US-4464455-A Dry-developing negative resist composition FUJITSU LIMITED (JP) 1984-08-07 US claimed
EP-0067067-A2 Dry-developing negative resist composition FUJITSU LIMITED (JP) 1982-12-15 EP claimed
EP-0067066-A2 Dry-developing resist composition FUJITSU LIMITED (JP) 1982-12-15 EP claimed
CN-111727271-B Method for producing metal-containing films 巴斯夫欧洲公司 2024-04-02 CN disclosed
WO-2024053557-A1 NON-AQUEOUS ELECTROLYTIC SOLUTION AND BATTERY 株式会社日本触媒 2024-03-14 WO disclosed
US-20230253626-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS ELECTROLYTIC SOLUTION SECONDARY BATTERY USING SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2023-08-10 US disclosed
US-4464455-A Dry-developing negative resist composition FUJITSU LIMITED (JP) 1984-08-07 US disclosed
EP-0067067-A2 Dry-developing negative resist composition FUJITSU LIMITED (JP) 1982-12-15 EP disclosed
EP-0067066-A2 Dry-developing resist composition FUJITSU LIMITED (JP) 1982-12-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110237793-A1 PROCESS FOR PREPARING ANTIVIRAL COMPOUND ZC3HAV1, HAVCR2, MAVS ESR1 4107/4885ESR2 4631/4885TSHR 4663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.