Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 17/20 | 0.62 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27311886 | 0.86 | CCR1 (0.69) | CCR1MDM2NR1I2TP53 | |
| SCHEMBL18895928 | 0.79 | CCR1 (0.57) | CCR1MDM2NR1I2TP53 | |
| SCHEMBL438488 | 0.76 | CCR1 (1.00) | CCR1MDM2NR1I2TP53 | |
| SCHEMBL403450 | 0.76 | CCR1 (1.00) | CCR1MDM2NR1I2TP53 | |
| SCHEMBL12121747 | 0.76 | CCR1 (1.00) | CCR1MDM2NR1I2TP53 | |
| SCHEMBL653493 | 0.76 | CCR1 (1.00) | CCR1MDM2NR1I2TP53 | |
| SCHEMBL438265 | 0.76 | CCR1 (1.00) | CCR1MDM2NR1I2TP53 | |
| SCHEMBL438487 | 0.76 | CCR1 (1.00) | CCR1MDM2NR1I2TP53 | |
| SCHEMBL13620905 | 0.76 | CCR1 (1.00) | CCR1MDM2NR1I2TP53 | |
| SCHEMBL653494 | 0.76 | CCR1 (1.00) | CCR1MDM2NR1I2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448566-A2 | CHEMOKINE RECEPTOR ANTAGONISTS AND METHODS OF USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003045942-A2 | CHEMOKINE RECEPTOR ANTAGONISTS AND METHODS OF USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2003-06-05 | — | — | WO | disclosed |