SCHEMBL6858261

SCHEMBL6858261

O=C(O)C1[CH]C(C(=O)O)C(C(=O)O)C1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 5/20 0.39
GRM2 Q14416 3/20 0.33
GABRR2 P28476 1/20 0.33
SLC1A2 P43004 3/20 0.31
GRM3 Q14832 2/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
GRM8 O00222 1/20 0.31
GRM6 O15303 1/20 0.31
LMNA P02545 1/20 0.31
APEX1 P27695 1/20 0.31
GRM5 P41594 1/20 0.31
PMP22 Q01453 1/20 0.31
GRM1 Q13255 1/20 0.31
GRM4 Q14833 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
SLC1A1 P43005 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL818222 0.79 GABRR1 (0.37) GABRR1GRM2GABRR2SLC1A2GRM3
SCHEMBL284782 0.68 GABRR1 (0.36) GABRR1GRM2GABRR2GRM3LMNA
SCHEMBL21085036 0.67 ABAT (0.41) GABRR1SLC1A2CYP2C19LMNAPMP22
SCHEMBL27825601 0.67 GABRR1 (0.34) GABRR1GRM2GABRR2GRM3LMNA
SCHEMBL27438497 0.64 POLB (0.44) GABRR1GRM2GABRR2GRM3LMNA
SCHEMBL31061861 0.64 GABRR1 (0.46) GABRR1GRM2GABRR2SLC1A2GRM3
SCHEMBL3404693 0.63 GABRR1 (0.59) GABRR1GRM2GABRR2SLC1A2GRM3
SCHEMBL709492 0.63 GABRR1 (0.59) GABRR1GABRR2SLC1A2CYP2C9CYP2C19
SCHEMBL15444681 0.63
SCHEMBL8495522 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021049255-A1 LIQUID CRYSTAL ORIENTATION AGENT, LIQUID CRYSTAL ORIENTATION FILM, AND LIQUID CRYSTAL ELEMENT JSR株式会社 2021-03-18 WO disclosed
EP-2534191-B1 PHOTOALIGNING MATERIAL WITH LATERAL SUBSTITUTION ROLIC TECH AG (CH) 2020-04-15 EP disclosed
EP-3076233-B1 POLYMERIC ALIGNMENT LAYERS IN A CURVED VERTICALLY-ALIGNED LIQUID CRYSTAL DISPLAY SAMSUNG DISPLAY CO LTD (KR) 2020-04-15 EP disclosed
US-9885914-B2 Liquid crystal display having different upper and lower alignment layers SAMSUNG DISPLAY CO., LTD. (KR) 2018-02-06 US disclosed
EP-3076233-A2 POLYMERIC ALIGNMENT LAYERS IN A CURVED VERTICALLY-ALIGNED LIQUID CRYSTAL DISPLAY Samsung Display Co., Ltd. (KR) 2016-10-05 EP disclosed
US-20160266420-A1 LIQUID CRYSTAL DISPLAY HAVING DIFFERENT UPPER AND LOWER ALIGNMENT LAYERS TCL CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2016-09-15 US disclosed
CN-105647181-A Composition for flexible substrate and flexible substrate 奇美实业股份有限公司 2016-06-08 CN disclosed
CN-101382703-B Liquid crystal aligning agent and liquid crystal display element JSR CORP 2011-11-09 CN disclosed
CN-101382703-A Liquid crystal aligning agent and liquid crystal display element JSR CORP (JP) 2009-03-11 CN disclosed
US-6783803-B2 A CONSTANT QUANTITY OF A COATING SOLUTION IS SUPPLIED INTERMITTENTLY; EXCELLENT IN UNIFORMITY OF FILM THICKNESS TORAY INDUSTRIES, INC. (JP) 2004-08-31 US disclosed
US-6641670-B2 Leaf coater for producing leaf type coated substrates TORAY INDUSTRIES, INC. (JP) 2003-11-04 US disclosed
US-20030170379-A1 Leaf coater and method for producing leaf type coated substrates TORAY INDUSTRIES, INC. (JP) 2003-09-11 US disclosed
US-20020078890-A1 Leaf coater and method for producing leaf type coated substrates TORAY INDUSTRIES, INC., A CORPORATION OF JAPAN (JP) 2002-06-27 US disclosed