SCHEMBL6858329

SCHEMBL6858329

O=C(OC1CCN[C@@H]1C(=O)O)C1CC(O)CN1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC1A2 P43004 3/20 0.39
DPP4 P27487 4/20 0.35
DPP8 Q6V1X1 4/20 0.35
DPP9 Q86TI2 4/20 0.35
MEN1 O00255 1/20 0.33
BLM P54132 1/20 0.33
KMT2A Q03164 1/20 0.33
SLC1A1 P43005 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
ALOX15 P16050 1/20 0.32
CYP2C19 P33261 1/20 0.32
SLC1A3 P43003 1/20 0.32
ARG1 P05089 3/20 0.31
ARG2 P78540 1/20 0.31
SMYD3 Q9H7B4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16397907 0.79 SLC1A2 (0.32) SLC1A2
SCHEMBL1491950 0.77 MEN1 (0.47) SLC1A2DPP4DPP8DPP9MEN1
SCHEMBL3262655 0.76 SLC1A2 (0.44) SLC1A2MEN1BLMKMT2AARG1
SCHEMBL2034433 0.76 SLC1A2 (0.44) SLC1A2MEN1BLMKMT2AARG1
SCHEMBL6515403 0.76 MEN1 (0.42) SLC1A2DPP4DPP8DPP9MEN1
SCHEMBL2029987 0.72 CYP2D6 (0.43) SLC1A2DPP4DPP8DPP9MEN1
SCHEMBL2029661 0.72 CYP2D6 (0.43) SLC1A2DPP4DPP8DPP9MEN1
SCHEMBL2031639 0.72 CYP2D6 (0.43) SLC1A2DPP4DPP8DPP9MEN1
SCHEMBL7293342 0.72 CYP2D6 (0.43) SLC1A2DPP4DPP8DPP9MEN1
SCHEMBL7594974 0.72 CYP2D6 (0.43) SLC1A2DPP4DPP8DPP9MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6835808-B2 Synthetic oligopeptide heparin-neutralizing agents including basic amino acids and a N-heterocyclic end group; low turbidity; side effects reduction; in vitro diagnosis; calculate the blood clotting time; assaying clotting cascade DIAGNOSTICA-STAGO (FR) 2004-12-28 US disclosed