SCHEMBL6515403

SCHEMBL6515403

O=C(OC1CCN[C@@H]1C(=O)O)C1CCCCN1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.42
BLM P54132 1/20 0.42
KMT2A Q03164 1/20 0.42
SLC1A2 P43004 1/20 0.41
ARG1 P05089 5/20 0.36
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
TSHR P16473 1/20 0.34
ARG2 P78540 1/20 0.33
DPP4 P27487 1/20 0.32
DPP8 Q6V1X1 1/20 0.32
DPP9 Q86TI2 1/20 0.32
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1491950 0.95 MEN1 (0.47) MEN1BLMKMT2ASLC1A2ARG1
Glycine SCHEMBL1675339 0.87 MEN1 (0.41) MEN1BLMKMT2ASLC1A2ARG1
Serine SCHEMBL5144903 0.82 MEN1 (0.36) MEN1BLMKMT2ASLC1A2ARG1
SCHEMBL4398036 0.80 MEN1 (0.35) MEN1BLMKMT2ASLC1A2ARG1
SCHEMBL6858329 0.76 SLC1A2 (0.39) MEN1BLMKMT2ASLC1A2ARG1
SCHEMBL27795961 0.76 NOS2 (0.38) CYP3A4CYP2D6CYP2C9TSHRDPP4
SCHEMBL27796013 0.76 NOS2 (0.38) CYP3A4CYP2D6CYP2C9TSHRDPP4
SCHEMBL2034433 0.76 SLC1A2 (0.44) MEN1BLMKMT2ASLC1A2ARG1
SCHEMBL3262655 0.76 SLC1A2 (0.44) MEN1BLMKMT2ASLC1A2ARG1
SCHEMBL22621401 0.74 MEN1 (0.41) MEN1BLMKMT2ASLC1A2ARG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1505955-A1 SHORT CHAIN POLYMER FOR ENHANCING THE BIOADHESIVENESS OF POLYMERS ON MUCOSAL MEMBRANE BROWN UNIVERSITY RESEARCH FOUNDATION (US) 2005-02-16 EP disclosed
WO-2003097015-A1 SHORT CHAIN POLYMER FOR ENHANCING THE BIOADHESIVENESS OF POLYMERS ON MUCOSAL MEMBRANE BROWN UNIVERSITY RESEARCH FOUNDATION (US) 2003-11-27 WO disclosed
US-20030077317-A1 Methods and compositions for enhancing the bioadhesive properties of polymers using organic excipients BROWN UNIVERSITY RESEARCH FOUNDATION 2003-04-24 US disclosed