Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Ammonia Solution, Strong. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8856001 | 0.82 | CYP3A4 (0.33) | — | |
| Hydrochloric Acid SCHEMBL11515885 | 0.82 | CYP3A4 (0.33) | — | |
| Hydrochloric Acid SCHEMBL15400 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL121448 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL7511711 | 0.82 | CYP3A4 (0.33) | — | |
| Hydrochloric Acid SCHEMBL10655988 | 0.82 | CYP3A4 (0.33) | — | |
| Hydrochloric Acid SCHEMBL10409095 | 0.82 | CYP3A4 (0.33) | — | |
| Ammonia Solution, Strong SCHEMBL23930398 | 0.67 | — | — | |
| Ammonia Solution, Strong SCHEMBL8651565 | 0.67 | — | — | |
| Ammonia Solution, Strong SCHEMBL817608 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4595774-A | Adding expanded graphite to reactive medium | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1986-06-17 | — | — | US | claimed |
| US-4177152-A | Method of extinguishing metal fires | CECA S.A. (FR) | 1979-12-04 | — | — | US | claimed |
| CN-114921664-B | Method for extracting germanium from low-grade germanium concentrate | 云南临沧鑫圆锗业股份有限公司 | 2024-02-02 | — | — | CN | disclosed |
| US-6790390-B2 | Composite material comprising activated carbon and expanded graphite | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2004-09-14 | — | — | US | disclosed |
| US-20030003289-A1 | Composite material comprising activated carbon and expanded graphite | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2003-01-02 | — | — | US | disclosed |
| US-4595774-A | Adding expanded graphite to reactive medium | SOCIETE NATIONALE ELF AQUITAINE (FR) | 1986-06-17 | — | — | US | disclosed |
| US-4177152-A | Method of extinguishing metal fires | CECA S.A. (FR) | 1979-12-04 | — | — | US | disclosed |
| US-4122119-A | Process for the production of unsaturated ketones | KURARAY CO., LTD. (JP) | 1978-10-24 | — | — | US | disclosed |