SCHEMBL6858460

SCHEMBL6858460

CC(C)(C)c1ccc(O)c(C([O])=O)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.60
HSP90AB1 P08238 1/20 0.60
ALDH1A1 P00352 2/20 0.57
TDP1 Q9NUW8 2/20 0.57
HSD17B10 Q99714 2/20 0.57
HPGD P15428 1/20 0.57
ALOX15 P16050 1/20 0.57
MAPT P10636 3/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
GAA P10253 1/20 0.52
PKM P14618 1/20 0.52
RECQL P46063 1/20 0.52
PLG P00747 2/20 0.50
KLK1 P06870 2/20 0.50
KLK6 Q92876 2/20 0.50
KLKB1 P03952 1/20 0.50
SIRT1 Q96EB6 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.45
LMNA P02545 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6581882 0.84 HSP90AA1 (0.60) HSP90AA1HSP90AB1ALDH1A1TDP1HSD17B10
SCHEMBL134234 0.84 HSP90AA1 (0.60) HSP90AA1HSP90AB1ALDH1A1TDP1HSD17B10
SCHEMBL20968011 0.84 HSP90AA1 (0.60) HSP90AA1HSP90AB1ALDH1A1TDP1HSD17B10
SCHEMBL427276 0.82 HSP90AA1 (0.58) HSP90AA1HSP90AB1ALDH1A1TDP1HSD17B10
SCHEMBL9636447 0.82 HSP90AA1 (0.58) HSP90AA1HSP90AB1ALDH1A1TDP1HSD17B10
Hydrochloric Acid SCHEMBL10933935 0.82 HSP90AA1 (0.58) HSP90AA1HSP90AB1ALDH1A1TDP1HSD17B10
SCHEMBL432204 0.82 HSP90AA1 (0.58) HSP90AA1HSP90AB1ALDH1A1TDP1HSD17B10
SCHEMBL1912762 0.82 HSP90AA1 (0.58) HSP90AA1HSP90AB1ALDH1A1TDP1HSD17B10
SCHEMBL7087682 0.82 HSP90AA1 (0.58) HSP90AA1HSP90AB1ALDH1A1TDP1HSD17B10
SCHEMBL10933923 0.82 HSP90AA1 (0.58) HSP90AA1HSP90AB1ALDH1A1TDP1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6783913-B2 POLYMERIC ACETAL RESIN CONTAINS UNITS (A), (B), (C), (D), AND (E). UNIT (A) IS A VINYL ALCOHOL UNIT. UNIT; (B) IS A POLYVINYL ACETAL UNIT CONTAINING AN R GROUP, WHERE R IS HYDROGEN, AN ALIPHATIC GROUP, AN AROMATIC GROUP, OR AN KODAK POLYCHROME GRAPHICS LLC 2004-08-31 US claimed
US-20030198887-A1 Polymeric acetal resins containing free radical inhibitors and their use in lithographic printing EASTMAN KODAK COMPANY 2003-10-23 US claimed
EP-1350801-A1 Polymeric acetal resins containing free radical inhibitors and their use in lithographic printing Kodak Polychrome Graphics GmbH (DE) 2003-10-08 EP claimed