SCHEMBL7087682

SCHEMBL7087682

CC(C)(C)c1ccc(O)c(C(=O)O)c1.[Zn]

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.58
HSP90AB1 P08238 1/20 0.58
PTPN5 P54829 1/20 0.56
TDP1 Q9NUW8 3/20 0.56
ALDH1A1 P00352 4/20 0.55
HSD17B10 Q99714 3/20 0.55
HPGD P15428 3/20 0.55
ALOX15 P16050 2/20 0.55
MEN1 O00255 5/20 0.55
KMT2A Q03164 5/20 0.55
KDM4E B2RXH2 3/20 0.55
MAPT P10636 2/20 0.55
CSNK2A1 P68400 1/20 0.55
POLB P06746 1/20 0.55
CYP2D6 P10635 1/20 0.55
ATM Q13315 1/20 0.55
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
PTGS2 P35354 2/20 0.53
CA12 O43570 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL134234 0.98 HSP90AA1 (0.60) HSP90AA1HSP90AB1PTPN5TDP1ALDH1A1
SCHEMBL432204 0.96 HSP90AA1 (0.58) HSP90AA1HSP90AB1PTPN5TDP1ALDH1A1
SCHEMBL427276 0.96 HSP90AA1 (0.58) HSP90AA1HSP90AB1PTPN5TDP1ALDH1A1
Hydrochloric Acid SCHEMBL10933935 0.96 HSP90AA1 (0.58) HSP90AA1HSP90AB1PTPN5TDP1ALDH1A1
SCHEMBL9769784 0.88 ACMSD (0.63) HSP90AA1HSP90AB1PTPN5TDP1ALDH1A1
SCHEMBL9244550 0.86 CSNK2A1 (0.57) HSP90AA1HSP90AB1PTPN5TDP1ALDH1A1
SCHEMBL9755159 0.86 CSNK2A1 (0.57) HSP90AA1HSP90AB1PTPN5TDP1ALDH1A1
SCHEMBL10915761 0.85 TDP1 (0.56) HSP90AA1HSP90AB1PTPN5TDP1ALDH1A1
SCHEMBL10464291 0.85 CSNK2A1 (0.55) HSP90AA1HSP90AB1PTPN5TDP1ALDH1A1
SCHEMBL9450718 0.83 ALDH1A1 (0.58) HSP90AA1HSP90AB1PTPN5TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030191023-A1 Thermosensitive recording material FUJI PHOTO FILM CO., LTD. 2003-10-09 US claimed
JP-54127951-A None JP disclosed
EP-0530663-B1 Heat sensitive recording material HODOGAYA CHEMICAL CO LTD (JP) 1996-11-06 EP disclosed
EP-0376318-B1 Thermosensitive recording member KAO CORP (JP) 1994-03-09 EP disclosed
US-5240898-A Colorless, or light-colored, electron donative dyestuff, acidic reactant, binder and arylthionaphthalene compound HODOGAYA CHEMICAL CO., LTD. (JP) 1993-08-31 US disclosed
EP-0530663-A1 Heat sensitive recording material HODOGAYA CHEMICAL CO., LTD. (JP) 1993-03-10 EP disclosed
US-5091356-A Comprising a substrate, a foamed dispersion layer of a self-emulsifiable resin, and a thermosensitive coloring layer containing a developer; stability; colorfastness; intensity KAO CORPORATION (JP) 1992-02-25 US disclosed
US-4996183-A Minimization of head stain MITSUBISHI PAPER MILLS, LIMITED (JP) 1991-02-26 US disclosed
US-4988663-A HEAT SENSITIVE RECORDING PAPER FOR COMPUTERS, MULTILAYER COATINGS OF POLYMERS, COLORING KAO CORPORATION (JP) 1991-01-29 US disclosed
EP-0376318-A2 Thermosensitive recording member KAO CORPORATION (JP) 1990-07-04 EP disclosed
US-4820550-A DISSOLVING, EMULSIFICATION, SLURRYING KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1989-04-11 US disclosed
EP-0304936-A2 Heat sensitive paper Kao Corporation (JP) 1989-03-01 EP disclosed
EP-0265190-A2 Process for producing a sheet of color-developer for pressure-sensitive recording paper KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1988-04-27 EP disclosed
US-4707463-A DYES, DEVELOPERS, SENSITIZERS MITSUBISHI PAPER MILLS, LTD. (JP) 1987-11-17 US disclosed
US-4557618-A PHENOLIC DEVELOPER AND ELECTRON DONATING COLORLESS DYE; DESENSITIZING COMPOUND PENTEL KABUSHIKI KAISHA (JP) 1985-12-10 US disclosed
JP-S54127951-A STABILIZATION OF VINYL CHLORIDE RESIN YOSHITOMI PHARMACEUT IND LTD 1979-10-04 JP disclosed