Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SGPL1 | O95470 | 6/20 | 0.42 |
| ▸ | SMO | Q99835 | 5/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.37 |
| ▸ | JAK1 | P23458 | 2/20 | 0.37 |
| ▸ | TYK2 | P29597 | 2/20 | 0.37 |
| ▸ | JAK3 | P52333 | 2/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6859229 | 1.00 | HDAC1 (0.47) | HDAC1KDM4EALDH1A1L3MBTL1SGPL1 | |
| SCHEMBL3599737 | 1.00 | HDAC1 (0.47) | HDAC1KDM4EALDH1A1L3MBTL1SGPL1 | |
| SCHEMBL23232261 | 0.85 | SGPL1 (0.45) | HDAC1KDM4EALDH1A1L3MBTL1SGPL1 | |
| SCHEMBL23744665 | 0.82 | ROCK2 (0.39) | HDAC1KDM4EALDH1A1L3MBTL1CHRM1 | |
| SCHEMBL23744666 | 0.82 | ROCK2 (0.39) | HDAC1KDM4EALDH1A1L3MBTL1CHRM1 | |
| SCHEMBL23744674 | 0.82 | ROCK2 (0.39) | HDAC1KDM4EALDH1A1L3MBTL1CHRM1 | |
| SCHEMBL26087094 | 0.82 | ROCK2 (0.39) | HDAC1KDM4EALDH1A1L3MBTL1CHRM1 | |
| SCHEMBL1108652 | 0.80 | HDAC1 (0.51) | HDAC1TLR9TLR8TLR7 | |
| SCHEMBL23744785 | 0.80 | HDAC1 (0.41) | HDAC1JAK2JAK1TYK2JAK3 | |
| SCHEMBL14612946 | 0.80 | SGPL1 (0.47) | KDM4EALDH1A1L3MBTL1SGPL1SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040010037-A1 | Cyanophenyl derivative | YAMANOUCHI PHARMACEUTICAL CO., LTD. | 2004-01-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040010037-A1 | Cyanophenyl derivative | BPHL, AR, KLK3 | HDAC1 64/4885KDM4E 892/4885ALDH1A1 1496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.