Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 14/20 | 0.64 |
| ▸ | ADORA1 | P30542 | 11/20 | 0.64 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.47 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6859506 | 0.92 | ADORA2A (0.62) | ADORA2AADORA1ADORA2BNPC1RAB9A | |
| SCHEMBL6859739 | 0.89 | ADORA2A (0.59) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6859611 | 0.88 | ADORA2A (0.58) | ADORA2AADORA1ADORA2BNPC1RAB9A | |
| SCHEMBL6859687 | 0.88 | ADORA2A (0.58) | ADORA2AADORA1ADORA2BNPC1RAB9A | |
| SCHEMBL6859714 | 0.86 | ADORA2A (0.53) | ADORA2AADORA1ADORA2BALDH1A1 | |
| SCHEMBL6858307 | 0.84 | ADORA2A (0.56) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6852934 | 0.84 | ADORA2A (0.56) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6858208 | 0.83 | ADORA2A (0.58) | ADORA2AADORA1ADORA2BSMN1; SMN2 | |
| SCHEMBL6858206 | 0.83 | ADORA2A (0.58) | ADORA2AADORA1ADORA2BSMN1; SMN2 | |
| SCHEMBL6852762 | 0.80 | ADORA2A (0.59) | ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787541-B1 | MOVEMENT DISORDERS, PARKINSON'S DISEASE | VERNALIS RESEARCH LIMITED (GB) | 2004-09-07 | — | — | US | disclosed |