Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 13/20 | 0.65 |
| ▸ | ADORA1 | P30542 | 12/20 | 0.65 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6859469 | 0.81 | ADORA2A (0.72) | ADORA2AADORA1 | |
| SCHEMBL6214990 | 0.80 | ADORA2A (1.00) | ADORA2AADORA1 | |
| SCHEMBL6859720 | 0.79 | ADORA2A (1.00) | ADORA2AADORA1NPC1RAB9AMAPT | |
| SCHEMBL6859875 | 0.78 | ADORA2A (1.00) | ADORA2AADORA1 | |
| SCHEMBL6859685 | 0.76 | ADORA2A (0.65) | ADORA2AADORA1 | |
| SCHEMBL6217242 | 0.75 | ADORA2A (1.00) | ADORA2AADORA1 | |
| SCHEMBL6859849 | 0.74 | ADORA2A (0.71) | ADORA2AADORA1 | |
| SCHEMBL6859837 | 0.74 | ADORA2A (0.71) | ADORA2AADORA1 | |
| SCHEMBL6852965 | 0.74 | ADORA2A (1.00) | ADORA2AADORA1MEN1KMT2AALDH1A1 | |
| SCHEMBL6853006 | 0.73 | ADORA2A (1.00) | ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787541-B1 | MOVEMENT DISORDERS, PARKINSON'S DISEASE | VERNALIS RESEARCH LIMITED (GB) | 2004-09-07 | — | — | US | disclosed |