Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 12/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 11/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6858284 | 0.84 | ADORA2A (0.56) | ADORA2AADORA1ALDH1A1HTTADORA2B | |
| SCHEMBL6852717 | 0.74 | ADORA2A (0.56) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6852935 | 0.73 | ADORA2A (0.70) | ADORA2AADORA1MEN1KMT2AHTT | |
| SCHEMBL6852809 | 0.72 | ADORA2A (0.65) | ADORA2AADORA1ADORA2B | |
| SCHEMBL2565551 | 0.67 | ADORA2A (1.00) | ADORA2AADORA1HTTADORA2B | |
| SCHEMBL6859709 | 0.67 | ADORA2A (1.00) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6214522 | 0.67 | ADORA2A (0.71) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6215714 | 0.66 | ADORA2A (0.69) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6858356 | 0.65 | ADORA2A (0.55) | ADORA2AADORA1ADORA2B | |
| SCHEMBL6858354 | 0.65 | ADORA2A (0.55) | ADORA2AADORA1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787541-B1 | MOVEMENT DISORDERS, PARKINSON'S DISEASE | VERNALIS RESEARCH LIMITED (GB) | 2004-09-07 | — | — | US | disclosed |