Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.51 |
| ▸ | EPM2A | O95278 | 1/20 | 0.51 |
| ▸ | PTPRC | P08575 | 1/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | PTPRG | P23470 | 1/20 | 0.51 |
| ▸ | ACP1 | P24666 | 1/20 | 0.51 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.51 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.51 |
| ▸ | PTPN9 | P43378 | 1/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.51 |
| ▸ | DUSP22 | Q9NRW4 | 1/20 | 0.51 |
| ▸ | CDC14A | Q9UNH5 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30607509 | 0.83 | NPC1 (0.67) | FFAR1NPC1RAB9AAKR1C2AKR1C1 | |
| SCHEMBL28354531 | 0.81 | SLC16A3 (0.54) | FFAR1NPC1RAB9AACACB | |
| SCHEMBL6865706 | 0.81 | NPC1 (0.53) | PTPN1PTPN6PTPN11FFAR1NPC1 | |
| SCHEMBL2256468 | 0.79 | NPC1 (0.72) | FFAR1NPC1RAB9AAKR1C2AKR1C1 | |
| SCHEMBL29479413 | 0.79 | NPC1 (0.72) | FFAR1NPC1RAB9AAKR1C2AKR1C1 | |
| SCHEMBL403812 | 0.79 | APP (0.50) | PTPN22EPM2APTPRCPTPN2PTPN1 | |
| SCHEMBL6866183 | 0.79 | NPC1 (0.57) | FFAR1NPC1RAB9AMMP2MMP9 | |
| SCHEMBL28287280 | 0.78 | EPHX2 (0.48) | DHODHMRGPRX4AKR1C2AKR1C1IGF2BP2 | |
| SCHEMBL69187 | 0.77 | NPC1 (0.59) | PTPN11FFAR1NPC1RAB9AHNF4A | |
| SCHEMBL29120766 | 0.76 | FFAR1 (0.42) | PTPN22EPM2APTPRCPTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6812252-B2 | ACYLSULFONAMIDE DERIVATIVES CONTAINING FLUOROSUBSTITUTEDPHENYLETHYNYL GROUP HAVING A HYPOGLYCEMIC EFFECT AND FREE OF THE SIDE EFFECT | AJINOMOTO CO., INC. (JP) | 2004-11-02 | — | — | US | disclosed |
| US-20030181764-A1 | Acylsulfonamide derivatives | AJINOMOTO CO. INC (JP) | 2003-09-25 | — | — | US | disclosed |
| EP-1316548-A1 | ACYLSULFONAMIDE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2003-06-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030181764-A1 | Acylsulfonamide derivatives | DPP4, SLC5A2, GLP1R | PTPN22 1123/4885EPM2A 2261/4885PTPRC 2760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.