SCHEMBL69187

SCHEMBL69187

O=C(O)c1ccc(C#Cc2ccccc2C(=O)O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.59
RAB9A P51151 1/20 0.59
SLC16A3 O15427 6/20 0.55
RARB P10826 1/20 0.50
RARG P13631 1/20 0.50
FFAR1 O14842 4/20 0.49
HNF4A P41235 1/20 0.49
PTPN11 Q06124 1/20 0.47
TSHR P16473 2/20 0.45
DAO P14920 1/20 0.45
NAPRT Q6XQN6 1/20 0.45
ALDH1A1 P00352 1/20 0.45
ALOX15 P16050 1/20 0.45
CHRM2 P08172 1/20 0.44
S1PR1 P21453 1/20 0.44
FPR1 P21462 1/20 0.44
FPR3 P25089 1/20 0.44
GPR183 P32249 1/20 0.44
APLNR P35414 1/20 0.44
FFAR4 Q5NUL3 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30607509 0.93 NPC1 (0.67) NPC1RAB9ASLC16A3FFAR1HNF4A
SCHEMBL29479413 0.89 NPC1 (0.72) NPC1RAB9AFFAR1HNF4ANAPRT
SCHEMBL2256468 0.89 NPC1 (0.72) NPC1RAB9AFFAR1HNF4ANAPRT
SCHEMBL8154163 0.88 FFAR1 (0.63) NPC1RAB9ASLC16A3RARBRARG
SCHEMBL69321 0.84 ALDH1A1 (0.62) NPC1RAB9AFFAR1HNF4ATSHR
SCHEMBL29409566 0.84 ALDH1A1 (0.62) NPC1RAB9AFFAR1HNF4ATSHR
SCHEMBL6866183 0.84 NPC1 (0.57) NPC1RAB9ASLC16A3FFAR1HNF4A
SCHEMBL30011755 0.83 NPC1 (0.59) NPC1RAB9AFFAR1HNF4ANAPRT
SCHEMBL1535890 0.83 NPC1 (0.59) NPC1RAB9AFFAR1HNF4ANAPRT
SCHEMBL402518 0.82 RARB (0.62) SLC16A3RARBRARGFFAR1HNF4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150274886-A1 Crosslinkable Soluble Aromatic Polyester TICONA LLC 2015-10-01 US claimed
CN-108884242-B Prepreg product and composite product comprising fibres and a liquid crystalline thermoset precursor 阿罗特罗皮卡科技公司 2021-11-26 CN disclosed
US-11001013-B2 Pre-preg and composite products comprising fibers and a liquid crystal thermoset precursor ALLOTROPICA TECHNOLOGIES INC. (US) 2021-05-11 US disclosed
EP-3405513-B1 PRE-PREG AND COMPOSITE PRODUCTS COMPRISING FIBERS AND A LIQUID CRYSTAL THERMOSET PRECURSOR ALLOTROPICA TECH INC (US) 2020-03-18 EP disclosed
US-20190039331-A1 PRE-PREG AND COMPOSITE PRODUCTS COMPRISING FIBERS AND A LIQUID CRYSTAL THERMOSET PRECURSOR ALLOTROPICA TECHNOLOGIES INC. 2019-02-07 US disclosed
EP-3405513-A1 PRE-PREG AND COMPOSITE PRODUCTS COMPRISING FIBERS AND A LIQUID CRYSTAL THERMOSET PRECURSOR Allotropica Technologies Inc. (US) 2018-11-28 EP disclosed
US-20170267824-A1 PREPREG COMPOSITE CONTAINING A CROSSLINKED AROMATIC POLYESTER TICONA LLC 2017-09-21 US disclosed
WO-2017125887-A1 PRE-PREG AND COMPOSITE PRODUCTS COMPRISING FIBERS AND A LIQUID CRYSTAL THERMOSET PRECURSOR ALLOTROPICA TECHNOLOGIES INC. (US) 2017-07-27 WO disclosed
US-20150274886-A1 Crosslinkable Soluble Aromatic Polyester TICONA LLC 2015-10-01 US disclosed
US-9145519-B2 Crosslinkable aromatic polyester TICONA LLC (US) 2015-09-29 US disclosed
US-7049371-B2 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2006-05-23 US disclosed
US-20040002572-A1 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2004-01-01 US disclosed
EP-1333050-A1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2003-08-06 EP disclosed
EP-1327653-A1 HEAT-RESISTANT RESIN PRECURSOR, HEAT-RESISTANT RESIN AND INSULATING FILM AND SEMICONDUCTOR DEVICE SUMITOMO BAKELITE CO., LTD. (JP) 2003-07-16 EP disclosed
US-6518390-B2 Polybenzoxazole and crosslinking agent SUMITOMO BAKELITE COMPANY, LTD. (JP) 2003-02-11 US disclosed
US-20020013443-A1 Precursor of a heat resistant resin, heat resistant resin, insulating film and semiconductor device SUMITOMO BAKELITE CO., LTD. (JP) 2002-01-31 US disclosed
EP-0980016-A1 ALIGNING AGENT FOR LIQUID CRYSTAL Nissan Chemical Industries, Ltd. (JP) 2000-02-16 EP disclosed
US-4752642-A Ethynyl-containing aromatic polyamide resin THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1988-06-21 US disclosed
US-4663425-A LAMINATION, FABRICS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1987-05-05 US disclosed
US-4657708-A AROMATIC POLYAMIDE RESINS CYCLIZED INTO POLYIMIDINES WITHOUT EVOLUTION OF VOLATILES; LAMINATES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1987-04-14 US disclosed