Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL10624113 | 0.85 | TSHR (0.69) | TSHRALDH1A1LMNATP53 | |
| Alcohol SCHEMBL10548408 | 0.82 | TSHR (0.65) | TSHRALDH1A1LMNATP53 | |
| SCHEMBL4611308 | 0.81 | TSHR (0.55) | TSHR | |
| Formaldehyde SCHEMBL23753933 | 0.81 | TSHR (0.85) | TSHRALDH1A1LMNATP53 | |
| Ethylene SCHEMBL11260915 | 0.81 | TSHR (0.85) | TSHRALDH1A1LMNATP53 | |
| SCHEMBL1330876 | 0.80 | — | — | |
| SCHEMBL3775773 | 0.80 | TSHR (1.00) | TSHRALDH1A1LMNATP53 | |
| SCHEMBL3948099 | 0.80 | TSHR (1.00) | TSHRALDH1A1LMNATP53 | |
| SCHEMBL16123 | 0.80 | — | — | |
| SCHEMBL27592095 | 0.80 | TSHR (1.00) | TSHRALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800413-B2 | LOADING/REACTING HYDROPHILIC PYROGENIC SILICA WITH SILYLATING AGENT (METHYLTRICHLOROSILANE), THEN PURIFYING WITH INERT GAS | WACKER-CHEMIE GMBH (DE) | 2004-10-05 | — | — | US | disclosed |
| US-20030138715-A1 | Low-silanol silica | WACKER-CHEMIE GMBH (DE) | 2003-07-24 | — | — | US | disclosed |