Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10517566 | 0.84 | BCHE (0.54) | BCHEACHELMNATSHRTAAR1 | |
| SCHEMBL10517572 | 0.84 | BCHE (0.54) | BCHEACHELMNATSHRTAAR1 | |
| SCHEMBL3906686 | 0.83 | BCHE (0.55) | BCHEACHELMNATSHRTAAR1 | |
| SCHEMBL19249780 | 0.81 | BCHE (0.52) | BCHEACHELMNATSHRCTSL | |
| SCHEMBL27500080 | 0.81 | BCHE (0.52) | BCHEACHELMNATSHRCTSL | |
| SCHEMBL13759699 | 0.81 | BCHE (0.52) | BCHEACHELMNATSHRCTSL | |
| SCHEMBL26579183 | 0.80 | BCHE (0.45) | BCHEACHELMNATSHRTAAR1 | |
| SCHEMBL7915130 | 0.80 | BCHE (0.48) | BCHEACHELMNATSHR | |
| SCHEMBL7915133 | 0.80 | BCHE (0.48) | BCHEACHELMNATSHR | |
| SCHEMBL7915444 | 0.80 | BCHE (0.48) | BCHEACHELMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6790860-B2 | USEFUL AS INHIBITORS OF METALLOPROTEASES, E.G. ZINC PROTEASES; EFFECTIVE IN TREATING DISEASE STATES ASSOCIATED WITH VASOCONSTRICTION | HOFFMANN-LA ROCHE INC. | 2004-09-14 | — | — | US | disclosed |