Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 6/20 | 0.41 |
| ▸ | NOS1 | P29475 | 6/20 | 0.41 |
| ▸ | NOS2 | P35228 | 6/20 | 0.41 |
| ▸ | CTSC | P53634 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7915130 | 1.00 | BCHE (0.48) | BCHEACHELMNANOS3NOS1 | |
| SCHEMBL7915444 | 1.00 | BCHE (0.48) | BCHEACHELMNANOS3NOS1 | |
| SCHEMBL13759699 | 0.87 | BCHE (0.52) | BCHEACHELMNANOS3NOS1 | |
| SCHEMBL19249780 | 0.87 | BCHE (0.52) | BCHEACHELMNANOS3NOS1 | |
| SCHEMBL27500080 | 0.87 | BCHE (0.52) | BCHEACHELMNANOS3NOS1 | |
| Methyl Alcohol SCHEMBL27520381 | 0.86 | BCHE (0.49) | BCHEACHELMNANOS3NOS1 | |
| SCHEMBL16740671 | 0.81 | POLB (0.44) | CTSC | |
| SCHEMBL10517566 | 0.81 | BCHE (0.54) | BCHEACHELMNATSHR | |
| SCHEMBL10517572 | 0.81 | BCHE (0.54) | BCHEACHELMNATSHR | |
| SCHEMBL6860683 | 0.80 | BCHE (0.48) | BCHEACHELMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221865-B1 | INHIBITORS OF PROTEIN FARNESYLTRANSFERASE AND PROTEIN GERANYLGERANYLTRANSFERASE. | UNIVERSITY OF PITTSBURGH | 2001-04-24 | — | — | US | disclosed |