Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6860825 | 0.70 | MEN1 (0.44) | BLM | |
| SCHEMBL20011291 | 0.62 | GDA (0.31) | GDACYP3A4PMP22ALDH1A1LMNA | |
| SCHEMBL19152808 | 0.61 | GSK3B (0.47) | — | |
| SCHEMBL20011085 | 0.60 | GDA (0.32) | GDACYP3A4PMP22ALDH1A1LMNA | |
| SCHEMBL10104855 | 0.60 | GDA (0.32) | GDACYP3A4PMP22ALDH1A1LMNA | |
| SCHEMBL9885817 | 0.59 | SRC (0.33) | GDACYP3A4PMP22ALDH1A1LMNA | |
| SCHEMBL19153038 | 0.57 | GSK3B (0.56) | ALDH1A1MAPT | |
| SCHEMBL18342514 | 0.57 | — | — | |
| SCHEMBL17813545 | 0.56 | PDE3B (0.36) | DDB1CRBN | |
| SCHEMBL13177050 | 0.56 | GDA (0.32) | GDACYP3A4PMP22ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9610235-B2 | Methods and compositions to improve mechanical resistance of teeth | THEOCORP HOLDING CO., LLC (US) | 2017-04-04 | — | — | US | disclosed |
| US-9610235-B2 | Methods and compositions to improve mechanical resistance of teeth | THEOCORP HOLDING CO., LLC (US) | 2017-04-04 | — | — | US | disclosed |
| WO-2011100671-A2 | METHODS AND COMPOSITIONS TO IMPROVE MECHANICAL RESISTANCE OF TEETH | THEOCORP HOLDING CO., LLC (US) | 2011-08-18 | — | — | WO | disclosed |