Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10039865 | 0.71 | PIK3CD (0.30) | GDA | |
| SCHEMBL11987584 | 0.71 | ALDH1A1 (0.32) | GDAALDH1A1TSHR | |
| SCHEMBL2136936 | 0.67 | GDA (0.32) | GDACYP3A4PMP22ALDH1A1LMNA | |
| SCHEMBL20011085 | 0.67 | GDA (0.32) | GDACYP3A4PMP22ALDH1A1LMNA | |
| SCHEMBL19090554 | 0.62 | HCAR3 (0.31) | — | |
| SCHEMBL19090548 | 0.62 | BRD4 (0.39) | ALDH1A1TSHR | |
| SCHEMBL9910655 | 0.61 | GDA (0.33) | GDACYP3A4PMP22ALDH1A1LMNA | |
| SCHEMBL10104855 | 0.60 | GDA (0.32) | GDACYP3A4PMP22ALDH1A1LMNA | |
| SCHEMBL15624085 | 0.60 | — | — | |
| SCHEMBL31685444 | 0.58 | ALDH1A1 (0.38) | GDAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299371-A1 | HYDROXYL PURINE COMPOUNDS AND USE THEREOF | GUANGDONG ZHONGSHENG PHARMACEUTICAL CO., LTD (CN) | 2018-03-28 | — | — | EP | disclosed |