Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL688013 | 0.82 | CHRNA7 (0.46) | CHRNA7CYP1A2CYP2D6 | |
| SCHEMBL19942443 | 0.80 | CHRNA7 (0.47) | CHRNA7CYP1A2CYP2D6 | |
| SCHEMBL10911731 | 0.70 | CA1 (0.39) | CHRNA7 | |
| Hydrochloric Acid SCHEMBL32681174 | 0.68 | KMT2A (0.47) | CHRNA7 | |
| SCHEMBL16673968 | 0.68 | CHRNA7 (0.53) | CHRNA7CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL32681179 | 0.68 | CHRNA7 (0.43) | CHRNA7CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL2823880 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL32681177 | 0.67 | KMT2A (0.50) | CHRNA7 | |
| Hydrochloric Acid SCHEMBL32681176 | 0.67 | CHRNA7 (0.46) | CHRNA7CYP1A2CYP2D6 | |
| SCHEMBL10911713 | 0.67 | CHRNA7 (0.34) | CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6835282-B2 | Providing pulp slurry containing low-grade pulp selected from gound wood pulp, recycled pulp, and mixtures; adding a pre-flocculated filler to slurry; forming a paper web from winding web on a reel | GRAIN PROCESSING CORPORATION | 2004-12-28 | — | — | US | disclosed |
| US-6602389-B2 | Providing a pulp slurry, containing at least about 30% by dry pulp weight of a low-grade pulp, adding a preflocculated filler to the slurry, forming a paper web, winding the web on a reel | GRAIN PROCESSING CORPORATION | 2003-08-05 | — | — | US | disclosed |
| US-20020100564-A1 | Paper web with pre-flocculated filler incorporated therein | GRAIN PROCESSING CORPORATION (US) | 2002-08-01 | — | — | US | disclosed |
| US-20020088565-A1 | Providing a pulp slurry, containing at least about 30% by dry pulp weight of a low-grade pulp, adding a preflocculated filler to the slurry, forming a paper web, winding the web on a reel | GRAIN PROCESSING CORPORATION | 2002-07-11 | — | — | US | disclosed |
| WO-2002002870-A2 | PROCESS FOR PREPARING A PAPER WEB | GRAIN PROCESSING CORPORATION (US) | 2002-01-10 | — | — | WO | disclosed |
| EP-0994216-A1 | Process for preparing a paper web | GRAIN PROCESSING CORPORATION (US) | 2000-04-19 | — | — | EP | disclosed |
| US-4799964-A | SHEARING | GRAIN PROCESSING CORPORATION (US) | 1989-01-24 | — | — | US | disclosed |