Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 8/20 | 0.52 |
| ▸ | LCK | P06239 | 6/20 | 0.52 |
| ▸ | TEK | Q02763 | 5/20 | 0.52 |
| ▸ | HCK | P08631 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 3/20 | 0.50 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.50 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 5/20 | 0.49 |
| ▸ | EGFR | P00533 | 5/20 | 0.49 |
| ▸ | ABL2 | P42684 | 5/20 | 0.49 |
| ▸ | EIF2AK3 | Q9NZJ5 | 3/20 | 0.48 |
| ▸ | RET | P07949 | 1/20 | 0.48 |
| ▸ | KIF5B | P33176 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | CCDC6 | Q16204 | 1/20 | 0.48 |
| ▸ | NEK7 | Q8TDX7 | 2/20 | 0.48 |
| ▸ | RIPK2 | O43353 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6465116 | 0.99 | SRC (0.51) | SRCLCKTEKHCKKDR | |
| Hydrochloric Acid SCHEMBL7117935 | 0.95 | SRC (0.51) | SRCLCKTEKHCKKDR | |
| Hydrochloric Acid SCHEMBL7852175 | 0.95 | SRC (0.52) | SRCLCKTEKHCKKDR | |
| SCHEMBL6461905 | 0.92 | LCK (0.59) | SRCLCKTEKHCKKDR | |
| Hydrochloric Acid SCHEMBL6463957 | 0.89 | SRC (0.51) | SRCLCKTEKHCKKDR | |
| SCHEMBL6865226 | 0.89 | NEK7 (0.57) | SRCLCKTEKHCKKDR | |
| SCHEMBL6866209 | 0.89 | LCK (0.52) | SRCLCKTEKHCKKDR | |
| SCHEMBL6865988 | 0.89 | SRC (0.51) | SRCLCKTEKHCKKDR | |
| Hydrochloric Acid SCHEMBL6463398 | 0.88 | SRC (0.51) | SRCLCKTEKHCKKDR | |
| SCHEMBL6867031 | 0.88 | LCK (0.55) | SRCLCKTEKHCKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6713474-B2 | SERINE-THREONINE AND TYROSINE KINASE INHIBITORS | ABBOTT GMBH & CO. KG (DE) | 2004-03-30 | — | — | US | disclosed |
| US-20030153752-A1 | Pyrrolopyrimidines as therapeutic agents | ABBVIE DEUTSCHLAND GMBH & CO KG (DE) | 2003-08-14 | — | — | US | disclosed |
| EP-1114053-A1 | PYRROLOPYRIMIDINES AS PROTEIN KINASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2001-07-11 | — | — | EP | disclosed |
| WO-2000017203-A1 | PYRROLOPYRIMIDINES AS PROTEIN KINASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2000-03-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030153752-A1 | Pyrrolopyrimidines as therapeutic agents | FLT1, FLT4, TFPI | SRC 206/4885LCK 6/4885TEK 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.