Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 9/20 | 0.55 |
| ▸ | TEK | Q02763 | 4/20 | 0.55 |
| ▸ | SRC | P12931 | 4/20 | 0.55 |
| ▸ | HCK | P08631 | 1/20 | 0.55 |
| ▸ | EIF2AK3 | Q9NZJ5 | 3/20 | 0.52 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.51 |
| ▸ | KDR | P35968 | 2/20 | 0.51 |
| ▸ | RET | P07949 | 2/20 | 0.51 |
| ▸ | KIF5B | P33176 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | CCDC6 | Q16204 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | ABL2 | P42684 | 2/20 | 0.49 |
| ▸ | NEK7 | Q8TDX7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6861029 | 0.91 | LCK (0.59) | LCKTEKSRCHCKEIF2AK3 | |
| SCHEMBL6861291 | 0.88 | SRC (0.52) | LCKTEKSRCHCKEIF2AK3 | |
| Hydrochloric Acid SCHEMBL6465116 | 0.88 | SRC (0.51) | LCKTEKSRCHCKEIF2AK3 | |
| SCHEMBL6460272 | 0.86 | SRC (0.61) | LCKTEKSRCHCKEIF2AK3 | |
| SCHEMBL6460851 | 0.86 | RIPK2 (0.60) | LCKTEKSRCHCKEIF2AK3 | |
| SCHEMBL6461293 | 0.85 | SRC (0.54) | LCKTEKSRCHCKEIF2AK3 | |
| SCHEMBL6867037 | 0.85 | SRC (0.53) | LCKTEKSRCHCKEIF2AK3 | |
| Carbamic Acid SCHEMBL7852916 | 0.85 | SRC (0.60) | LCKTEKSRCHCKEIF2AK3 | |
| SCHEMBL6867280 | 0.84 | LCK (0.55) | LCKTEKSRCHCKEIF2AK3 | |
| SCHEMBL6461905 | 0.84 | LCK (0.59) | LCKTEKSRCHCKEIF2AK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6713474-B2 | SERINE-THREONINE AND TYROSINE KINASE INHIBITORS | ABBOTT GMBH & CO. KG (DE) | 2004-03-30 | — | — | US | disclosed |
| US-20030153752-A1 | Pyrrolopyrimidines as therapeutic agents | ABBVIE DEUTSCHLAND GMBH & CO KG (DE) | 2003-08-14 | — | — | US | disclosed |
| EP-1114053-A1 | PYRROLOPYRIMIDINES AS PROTEIN KINASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2001-07-11 | — | — | EP | disclosed |
| WO-2000017203-A1 | PYRROLOPYRIMIDINES AS PROTEIN KINASE INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2000-03-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030153752-A1 | Pyrrolopyrimidines as therapeutic agents | FLT1, FLT4, TFPI | LCK 6/4885TEK 22/4885SRC 206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.